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FLASH GENE
Symbol MT1E contributors: mct/npt - updated : 13-03-2009
HGNC name metallothionein 1E
HGNC id 7397
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated MetalloP
HOMOLOGY
Homologene
FAMILY
  • metallothionein superfamily
  • type 1 family
    • CATEGORY motor/contractile , storage
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in multiple protective pathways including binding of toxic metals, free radical scavenging, and oxidative stress (Oppermann 2001)
  • having a necessary role for cancer cell migration (Wu 2008)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • heavy metal ions
    • protein
    cell & other
    REGULATION
    induced by heavy metal ions
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in bladder cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS