| Other morbid association(s)
|
| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| tumoral
|
|
| --over
|
| |
in ovarian, colorectal and gastric cancer and higher expression of KLK10 closely correlates with advanced disease stage, which predicts a poorer prognosis | | tumoral
|
|
| --low
|
| |
in breast cancer (in progression), and in testicular cancer, in cervical cancer, prostate cancer and acute lymphocytic leukemia | | tumoral
|
|
| --over
|
|
in oral squamous cell carcinoma and may be implicated in malignant progression  | | tumoral
|
|
| --low
|
| |
in hepatocellular carcinoma by hypermethylation, significantly associated with cirrhosis and HCV infection as well as inversely associated with HBV infection | | constitutional
|
|
| --over
|
| |
significantly increased in Alzheimer disease | | tumoral
|
|
| --over
|
| |
increased KLK10 and KLK11 protein expression is associated with favorable prognosis in advanced high-grade serous ovarian cancer | |
