Citations for
1KLK10, KLK13, KLK7, KLK9
Kallikrein-related peptidases protein expression in lymphoid tissues suggests potential implications in immune response.
Filippou PS, Ren AH, Soosaipillai A, Safar R, Prassas I, Diamandis EP, Conner JR.
Clin Biochem 77:41-47. doi: 10.1016/j.clinbiochem.2019.12.015. Epub 2020 Jan 2. 2020
2KLK10, KLK6
Kallikrein-related peptidases 6 and 10 are elevated in cerebrospinal fluid of patients with Alzheimer's disease and associated with CSF-TAU and FDG-PET.
Goldhardt O, Warnhoff I, Yakushev I, Begcevic I, Förstl H, Magdolen V, Soosaipillai A, Diamandis E, Alexopoulos P, Grimmer T.
Transl Neurodegener 8:25. doi: 10.1186/s40035-019-0168-6. eCollection 2019. 2019
3BCL2L12, EMD, KLK10, LMNA, MYO1C, SMAD2
Lamin A/C and Emerin depletion impacts chromatin organization and dynamics in the interphase nucleus.
Ranade D, Pradhan R, Jayakrishnan M, Hegde S, Sengupta K.
BMC Mol Cell Biol 20(1):11. doi: 10.1186/s12860-019-0192-5. 2019
4ANKRD22, ARNTL2, CEP55, COL17A1, ITGB6, KLK10, MCOLN3, MET, SLC25A45
Identification of a Nine-Gene Signature and Establishment of a Prognostic Nomogram Predicting Overall Survival of Pancreatic Cancer
Wu M, Li X, Zhang T, Liu Z, Zhao Y.
Front Oncol. Sep 27;9:996. doi: 10.3389/fonc.2019.00996 2019
5KLK10, KLK11
Elevated tumor tissue protein expression levels of kallikrein-related peptidases KLK10 and KLK11 are associated with a better prognosis in advanced high-grade serous ovarian cancer patients.
Geng X, Liu Y, Dreyer T, Bronger H, Drecoll E, Magdolen V, Dorn J.
Am J Cancer Res 8(9):1856-1864. eCollection 2018. 2018
6KLK10, KLK15, KLK2, KLK3, KLK6, KLK7, KLK8
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Tailor PD, Kodeboyina SK, Bai S, Patel N, Sharma S, Ratnani A, Copland JA, She JX, Sharma A.
Oncotarget 9(25):17876-17888. doi: 10.18632/oncotarget.24947. eCollection 2018 Apr 3. 2018
7KLK10
KLK10 exon 3 unmethylated PCR product concentration: a new potential early diagnostic marker in ovarian cancer? - A pilot study.
El Sherbini MA, Mansour AA, Sallam MM, Shaban EA, Shehab ElDin ZA, El-Shalakany AH.
J Ovarian Res 11(1):32. doi: 10.1186/s13048-018-0407-y. 2018
8KLK10
Aberrant upregulation of KLK10 promotes metastasis via enhancement of EMT and FAK/SRC/ERK axis in PDAC.
Cao XY, Zhang XX, Yang MW, Hu LP, Jiang SH, Tian GA, Zhu LL, Li Q, Sun YW, Zhang ZG.
Biochem Biophys Res Commun 499(3):584-593. doi: 10.1016/j.bbrc.2018.03.194. Epub 2018 Apr 4. 2018
9KLK1, KLK10, KLK13, KLK14, KLK6
Functional interrelationships between the kallikrein-related peptidases family and the classical kinin system in the human neutrophil.
Ehrenfeld P, Bhoola KD, Matus CE, Figueroa CD.
Biol Chem 399(9):925-935. doi: 10.1515/hsz-2017-0338. Review. 2018
10KLK10
Identification and molecular cloning of novel transcripts of the human kallikrein-related peptidase 10 (KLK10) gene using next-generation sequencing.
Adamopoulos PG, Kontos CK, Scorilas A.
Biochem Biophys Res Commun 487(4):776-781. doi: 10.1016/j.bbrc.2017.04.078. Epub 2017 Apr 15. 2017
11KLK10
NES1/KLK10 gene represses proliferation, enhances apoptosis and down-regulates glucose metabolism of PC3 prostate cancer cells.
Hu J, Lei H, Fei X, Liang S, Xu H, Qin D, Wang Y, Wu Y, Li B.
Sci Rep 5:17426. doi: 10.1038/srep17426. 2015
12KLK10, KLK6
Evaluation of human tissue kallikrein-related peptidases 6 and 10 expression in early gastroesophageal adenocarcinoma.
Grin A, Samaan S, Tripathi M, Rotondo F, Kovacs K, Bassily MN, Yousef GM.
Hum Pathol 46(4):541-8. doi: 10.1016/j.humpath.2014.12.005. Epub 2014 Dec 31. 2015
13KLK10, KLK6
Prognostic significance of human tissue kallikrein-related peptidases 6 and 10 in gastric cancer.
Kolin DL, Sy K, Rotondo F, Bassily MN, Kovacs K, Brezden-Masley C, Streutker CJ, Yousef GM.
Biol Chem 395(9):1087-93. doi: 10.1515/hsz-2014-0143. 2014
14KLK10
Kallikrein-related peptidase 10 expression in salivary gland tissues and tumours.
Darling MR, Hashem NN, Zhang I, Mohamed AB, Fung K, Kwan K, Mara TW, Daley TD, Diamandis EP.
Int J Biol Markers 27(4):e381-8. doi: 10.5301/JBM.2012.10373. 2012
15KLK10, KLK6
The association with age, human tissue kallikreins 6 and 10 and hemostatic markers for survival outcome from epithelial ovarian cancer.
Koh SC, Razvi K, Chan YH, Narasimhan K, Ilancheran A, Low JJ, Choolani M; Ovarian Cancer Research Consortium of SE Asia.
Arch Gynecol Obstet 284(1):183-90. doi: 10.1007/s00404-010-1605-z. Epub 2010 Aug 1. 2011
16KLK10, KLK5, KLK7, KLK8
Multiple kallikrein (KLK 5, 7, 8, and 10) expression in squamous cell carcinoma of the oral cavity.
Pettus JR, Johnson JJ, Shi Z, Davis JW, Koblinski J, Ghosh S, Liu Y, Ravosa MJ, Frazier S, Stack MS.
Histol Histopathol 24(2):197-207. 2009
17KLK10, KLK15, KLK9
A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15.
Yoon H, Blaber SI, Debela M, Goettig P, Scarisbrick IA, Blaber M.
Biol Chem 390(4):373-7.PMID: 19090718 2009
18KLK10, OXGR1
Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma.
Lu CY, Hsieh SY, Lu YJ, Wu CS, Chen LC, Lo SJ, Wu CT, Chou MY, Huang TH, Chang YS.
Genes Chromosomes Cancer 48(12):1057-68.PMID: 19760608 2009
19KLK10, KLK11, KLK14
Androgens act synergistically to enhance estrogen-induced upregulation of human tissue kallikreins 10, 11, and 14 in breast cancer cells via a membrane bound androgen receptor.
Paliouras M, Diamandis EP.
Mol Oncol 1(4):413-24. Epub 2008 Jan 9.PMID: 19383315 2008
20KLK10, KLK11, KLK14, KLK3
Intracellular signaling pathways regulate hormone-dependent kallikrein gene expression.
Paliouras M, Diamandis EP.
Tumour Biol 29(2):63-75. Epub 2008 Jun 2.PMID: 18515984 2008
21KLK10, KLK11
Expression of the human kallikrein genes 10 (KLK10) and 11 (KLK11) in cancerous and non-cancerous lung tissues.
Planque C, Ainciburu M, Heuze-Vourc'h N, Regina S, de Monte M, Courty Y.
Biol Chem 387(6):783-8. 2006
22KLK10
Clinical significance of human kallikrein 10 gene expression in colorectal cancer and gastric cancer.
Feng B, Xu WB, Zheng MH, Ma JJ, Cai Q, Zhang Y, Ji J, Lu AG, Qu Y, Li JW, Wang ML, Hu WG, Liu BY, Zhu ZG.
J Gastroenterol Hepatol 21(10):1596-603. 2006
23KLK10
Human kallikrein 10, a predictive marker for breast cancer.
Zhang Y, Bhat I, Zeng M, Jayal G, Wazer DE, Band H, Band V.
Biol Chem 387(6):715-21. Review. 2006
24KLK10
Identification of new splice variants and differential expression of the human kallikrein 10 gene, a candidate cancer biomarker.
Yousef GM, White NM, Michael IP, Cho JC, Robb JD, Kurlender L, Khan S, Diamandis EP.
Tumour Biol 26(5):227-35. Epub 2005 Aug 9. 2005
25KLK10
Expression of the normal epithelial cell-specific 1 (NES1; KLK10) candidate tumour suppressor gene in normal and malignant testicular tissue.
Luo LY, Rajpert-De Meyts ER, Jung K, Diamandis EP.
Br J Cancer 85(2):220-4. 2001
26KLK10, KLK11, KLK12, KLK13, KLK14, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
The New Human Kallikrein Gene Family: Implications in Carcinogenesis.
Diamandis EP, Yousef GM, Luo I, Magklara I, Obiezu CV.
Trends Endocrinol Metab 11(2):54-60. 2000
27KLK1, KLK10, KLK11, KLK12, KLK13, KLK2, KLK3, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4.
Harvey TJ, Hooper JD, Myers SA, Stephenson SA, Ashworth LK, Clements JA.
J Biol Chem 275(48):37397-406. 2000
28KLK10
Structural characterization and mapping of the normal epithelial cell-specific 1 gene.
Luo L, Herbrick JA, Scherer SW, Beatty B, Squire J, Diamandis EP.
Biochem Biophys Res Commun 247(3):580-6. 1998
29KLK10, PRSS57
Assignment of protease, serine-like 1 (PRSSL1) to human chromosome 19q13 by in situ hybridization and radiation hybrid mapping.
Polikoff D, Kuo WL, Cochran JF, Wernick M, Kowbel D, Myambo K, Collins CC.
Cytogenet Cell Genet 79(1-2):147-8. 1997
30KLK10
Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression.
Liu XL, et al.
Cancer Res 56 : 3371-3379. 1996