1 | KLK10, KLK13, KLK7, KLK9
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| Kallikrein-related peptidases protein expression in lymphoid tissues suggests potential implications in immune response.
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| Filippou PS, Ren AH, Soosaipillai A, Safar R, Prassas I, Diamandis EP, Conner JR.
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| Clin Biochem 77:41-47. doi: 10.1016/j.clinbiochem.2019.12.015. Epub 2020 Jan 2.
2020
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2 | KLK10, KLK6
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| Kallikrein-related peptidases 6 and 10 are elevated in cerebrospinal fluid of patients with Alzheimer's disease and associated with CSF-TAU and FDG-PET.
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| Goldhardt O, Warnhoff I, Yakushev I, Begcevic I, Förstl H, Magdolen V, Soosaipillai A, Diamandis E, Alexopoulos P, Grimmer T.
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| Transl Neurodegener 8:25. doi: 10.1186/s40035-019-0168-6. eCollection 2019.
2019
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3 | BCL2L12, EMD, KLK10, LMNA, MYO1C, SMAD2
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| Lamin A/C and Emerin depletion impacts chromatin organization and dynamics in the interphase nucleus.
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| Ranade D, Pradhan R, Jayakrishnan M, Hegde S, Sengupta K.
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| BMC Mol Cell Biol 20(1):11. doi: 10.1186/s12860-019-0192-5.
2019
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4 | ANKRD22, ARNTL2, CEP55, COL17A1, ITGB6, KLK10, MCOLN3, MET, SLC25A45
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| Identification of a Nine-Gene Signature and Establishment of a Prognostic Nomogram Predicting Overall Survival of Pancreatic Cancer
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| Wu M, Li X, Zhang T, Liu Z, Zhao Y.
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| Front Oncol. Sep 27;9:996. doi: 10.3389/fonc.2019.00996 2019
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5 | KLK10, KLK11
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| Elevated tumor tissue protein expression levels of kallikrein-related peptidases KLK10 and KLK11 are associated with a better prognosis in advanced high-grade serous ovarian cancer patients.
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| Geng X, Liu Y, Dreyer T, Bronger H, Drecoll E, Magdolen V, Dorn J.
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| Am J Cancer Res 8(9):1856-1864. eCollection 2018.
2018
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6 | KLK10, KLK15, KLK2, KLK3, KLK6, KLK7, KLK8
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| Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
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| Tailor PD, Kodeboyina SK, Bai S, Patel N, Sharma S, Ratnani A, Copland JA, She JX, Sharma A.
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| Oncotarget 9(25):17876-17888. doi: 10.18632/oncotarget.24947. eCollection 2018 Apr 3.
2018
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7 | KLK10
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| KLK10 exon 3 unmethylated PCR product concentration: a new potential early diagnostic marker in ovarian cancer? - A pilot study.
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| El Sherbini MA, Mansour AA, Sallam MM, Shaban EA, Shehab ElDin ZA, El-Shalakany AH.
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| J Ovarian Res 11(1):32. doi: 10.1186/s13048-018-0407-y.
2018
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8 | KLK10
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| Aberrant upregulation of KLK10 promotes metastasis via enhancement of EMT and FAK/SRC/ERK axis in PDAC.
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| Cao XY, Zhang XX, Yang MW, Hu LP, Jiang SH, Tian GA, Zhu LL, Li Q, Sun YW, Zhang ZG.
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| Biochem Biophys Res Commun 499(3):584-593. doi: 10.1016/j.bbrc.2018.03.194. Epub 2018 Apr 4.
2018
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9 | KLK1, KLK10, KLK13, KLK14, KLK6
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| Functional interrelationships between the kallikrein-related peptidases family and the classical kinin system in the human neutrophil.
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| Ehrenfeld P, Bhoola KD, Matus CE, Figueroa CD.
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| Biol Chem 399(9):925-935. doi: 10.1515/hsz-2017-0338. Review.
2018
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10 | KLK10
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| Identification and molecular cloning of novel transcripts of the human kallikrein-related peptidase 10 (KLK10) gene using next-generation sequencing.
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| Adamopoulos PG, Kontos CK, Scorilas A.
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| Biochem Biophys Res Commun 487(4):776-781. doi: 10.1016/j.bbrc.2017.04.078. Epub 2017 Apr 15.
2017
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11 | KLK10
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| NES1/KLK10 gene represses proliferation, enhances apoptosis and down-regulates glucose metabolism of PC3 prostate cancer cells.
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| Hu J, Lei H, Fei X, Liang S, Xu H, Qin D, Wang Y, Wu Y, Li B.
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| Sci Rep 5:17426. doi: 10.1038/srep17426.
2015
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12 | KLK10, KLK6
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| Evaluation of human tissue kallikrein-related peptidases 6 and 10 expression in early gastroesophageal adenocarcinoma.
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| Grin A, Samaan S, Tripathi M, Rotondo F, Kovacs K, Bassily MN, Yousef GM.
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| Hum Pathol 46(4):541-8. doi: 10.1016/j.humpath.2014.12.005. Epub 2014 Dec 31.
2015
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13 | KLK10, KLK6
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| Prognostic significance of human tissue kallikrein-related peptidases 6 and 10 in gastric cancer.
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| Kolin DL, Sy K, Rotondo F, Bassily MN, Kovacs K, Brezden-Masley C, Streutker CJ, Yousef GM.
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| Biol Chem 395(9):1087-93. doi: 10.1515/hsz-2014-0143.
2014
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14 | KLK10
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| Kallikrein-related peptidase 10 expression in salivary gland tissues and tumours.
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| Darling MR, Hashem NN, Zhang I, Mohamed AB, Fung K, Kwan K, Mara TW, Daley TD, Diamandis EP.
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| Int J Biol Markers 27(4):e381-8. doi: 10.5301/JBM.2012.10373.
2012
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15 | KLK10, KLK6
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| The association with age, human tissue kallikreins 6 and 10 and hemostatic markers for survival outcome from epithelial ovarian cancer.
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| Koh SC, Razvi K, Chan YH, Narasimhan K, Ilancheran A, Low JJ, Choolani M; Ovarian Cancer Research Consortium of SE Asia.
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| Arch Gynecol Obstet 284(1):183-90. doi: 10.1007/s00404-010-1605-z. Epub 2010 Aug 1.
2011
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16 | KLK10, KLK5, KLK7, KLK8
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| Multiple kallikrein (KLK 5, 7, 8, and 10) expression in squamous cell carcinoma of the oral cavity.
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| Pettus JR, Johnson JJ, Shi Z, Davis JW, Koblinski J, Ghosh S, Liu Y, Ravosa MJ, Frazier S, Stack MS.
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| Histol Histopathol 24(2):197-207.
2009
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17 | KLK10, KLK15, KLK9
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| A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15.
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| Yoon H, Blaber SI, Debela M, Goettig P, Scarisbrick IA, Blaber M.
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| Biol Chem 390(4):373-7.PMID: 19090718 2009
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18 | KLK10, OXGR1
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| Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma.
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| Lu CY, Hsieh SY, Lu YJ, Wu CS, Chen LC, Lo SJ, Wu CT, Chou MY, Huang TH, Chang YS.
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| Genes Chromosomes Cancer 48(12):1057-68.PMID: 19760608 2009
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19 | KLK10, KLK11, KLK14
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| Androgens act synergistically to enhance estrogen-induced upregulation of human tissue kallikreins 10, 11, and 14 in breast cancer cells via a membrane bound androgen receptor.
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| Paliouras M, Diamandis EP.
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| Mol Oncol 1(4):413-24. Epub 2008 Jan 9.PMID: 19383315 2008
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20 | KLK10, KLK11, KLK14, KLK3
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| Intracellular signaling pathways regulate hormone-dependent kallikrein gene expression.
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| Paliouras M, Diamandis EP.
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| Tumour Biol 29(2):63-75. Epub 2008 Jun 2.PMID: 18515984 2008
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21 | KLK10, KLK11
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| Expression of the human kallikrein genes 10 (KLK10) and 11 (KLK11) in cancerous and non-cancerous lung tissues.
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| Planque C, Ainciburu M, Heuze-Vourc'h N, Regina S, de Monte M, Courty Y.
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| Biol Chem 387(6):783-8. 2006
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22 | KLK10
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| Clinical significance of human kallikrein 10 gene expression in colorectal cancer and gastric cancer.
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| Feng B, Xu WB, Zheng MH, Ma JJ, Cai Q, Zhang Y, Ji J, Lu AG, Qu Y, Li JW, Wang ML, Hu WG, Liu BY, Zhu ZG.
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| J Gastroenterol Hepatol 21(10):1596-603. 2006
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23 | KLK10
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| Human kallikrein 10, a predictive marker for breast cancer.
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| Zhang Y, Bhat I, Zeng M, Jayal G, Wazer DE, Band H, Band V.
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| Biol Chem 387(6):715-21. Review. 2006
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24 | KLK10
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| Identification of new splice variants and differential expression of the human kallikrein 10 gene, a candidate cancer biomarker.
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| Yousef GM, White NM, Michael IP, Cho JC, Robb JD, Kurlender L, Khan S, Diamandis EP.
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| Tumour Biol 26(5):227-35. Epub 2005 Aug 9. 2005
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25 | KLK10
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| Expression of the normal epithelial cell-specific 1 (NES1; KLK10) candidate tumour suppressor gene in normal and malignant testicular tissue.
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| Luo LY, Rajpert-De Meyts ER, Jung K, Diamandis EP.
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| Br J Cancer 85(2):220-4. 2001
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26 | KLK10, KLK11, KLK12, KLK13, KLK14, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
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| The New Human Kallikrein Gene Family: Implications in Carcinogenesis.
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| Diamandis EP, Yousef GM, Luo I, Magklara I, Obiezu CV.
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| Trends Endocrinol Metab 11(2):54-60. 2000
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27 | KLK1, KLK10, KLK11, KLK12, KLK13, KLK2, KLK3, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
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| Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4.
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| Harvey TJ, Hooper JD, Myers SA, Stephenson SA, Ashworth LK, Clements JA.
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| J Biol Chem 275(48):37397-406.
2000
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28 | KLK10
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| Structural characterization and mapping of the normal epithelial cell-specific 1 gene.
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| Luo L, Herbrick JA, Scherer SW, Beatty B, Squire J, Diamandis EP.
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| Biochem Biophys Res Commun 247(3):580-6. 1998
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29 | KLK10, PRSS57
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| Assignment of protease, serine-like 1 (PRSSL1) to human chromosome 19q13 by in situ hybridization and radiation hybrid mapping.
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| Polikoff D, Kuo WL, Cochran JF, Wernick M, Kowbel D, Myambo K, Collins CC.
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| Cytogenet Cell Genet 79(1-2):147-8. 1997
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30 | KLK10
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| Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression.
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| Liu XL, et al.
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| Cancer Res 56 : 3371-3379. 1996
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