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FLASH GENE

Symbol

GRID2

contributors: mct - updated : 18-10-2016

HGNC name	glutamate receptor, ionotropic, delta 2
HGNC id	4576

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

SCAR18

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       loss of function disrupts the time course of GRM1-dependent synaptic transmission at parallel fiber-Purkinje cells synapses

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

	homozygous and heterozygous "lurcher" mice (Zuo, 97)
	GluRdelta2-/- mice display ataxia and impaired motor learning