Citations for
1CDC42, GOPC, GRID2
Potential of GRID2 receptor gene for preventing TNF-induced neurodegeneration in autism.
Kalkan Z, Durasi İM, Sezerman U, Atasever-Arslan B.
Neurosci Lett 620:62-9. doi: 10.1016/j.neulet.2016.03.043. Epub 2016 Mar 25. 2016
2GRID2, SCAR18
GRID2 mutations span from congenital to mild adult-onset cerebellar ataxia.
Coutelier M, Burglen L, Mundwiller E, Abada-Bendib M, Rodriguez D, Chantot-Bastaraud S, Rougeot C, Cournelle MA, Milh M, Toutain A, Bacq D, Meyer V, Afenjar A, Deleuze JF, Brice A, Héron D, Stevanin G, Durr A.
Neurology 84(17):1751-9. doi: 10.1212/WNL.0000000000001524. Epub 2015 Apr 3. 2015
3GRID2, MVKD
GRID2 a novel gene possibly associated with mevalonate kinase deficiency.
Moura R, Tricarico PM, Campos Coelho AV, Crovella S.
Rheumatol Int 35(4):657-9. doi: 10.1007/s00296-014-3115-y. Epub 2014 Aug 22. 2015
4GRID2, SCAR18
Early-onset autosomal recessive cerebellar ataxia associated with retinal dystrophy: new human hotfoot phenotype caused by homozygous GRID2 deletion.
Van Schil K, Meire F, Karlstetter M, Bauwens M, Verdin H, Coppieters F, Scheiffert E, Van Nechel C, Langmann T, Deconinck N, De Baere E.
Genet Med 17(4):291-9. doi: 10.1038/gim.2014.95. Epub 2014 Aug 14. 2015
5GRID2, SCAR18
GRID2 mutations span from congenital to mild adult-onset cerebellar ataxia.
Coutelier M, Burglen L, Mundwiller E, Abada-Bendib M, Rodriguez D, Chantot-Bastaraud S, Rougeot C, Cournelle MA, Milh M, Toutain A, Bacq D, Meyer V, Afenjar A, Deleuze JF, Brice A, Héron D, Stevanin G, Durr A.
Neurology 84(17):1751-9. doi: 10.1212/WNL.0000000000001524. Epub 2015 Apr 3. 2015
6GRID2
Type 1 metabotropic glutamate receptors (mGlu1) trigger the gating of GluD2 delta glutamate receptors.
Ady V, Perroy J, Tricoire L, Piochon C, Dadak S, Chen X, Dusart I, Fagni L, Lambolez B, Levenes C.
EMBO Rep 15(1):103-9. doi: 10.1002/embr.201337371. Epub 2013 Dec 15. 2014
7GRID2
A new mouse allele of glutamate receptor delta 2 with cerebellar atrophy and progressive ataxia.
Miyoshi Y, Yoshioka Y, Suzuki K, Miyazaki T, Koura M, Saigoh K, Kajimura N, Monobe Y, Kusunoki S, Matsuda J, Watanabe M, Hayasaka N.
PLoS One 9(9):e107867. doi: 10.1371/journal.pone.0107867. eCollection 2014. 2014
8GRID2, SCAR18
Deletions in GRID2 lead to a recessive syndrome of cerebellar ataxia and tonic upgaze in humans.
Hills LB, Masri A, Konno K, Kakegawa W, Lam AT, Lim-Melia E, Chandy N, Hill RS, Partlow JN, Al-Saffar M, Nasir R, Stoler JM, Barkovich AJ, Watanabe M, Yuzaki M, Mochida GH.
Neurology 81(16):1378-86. doi: 10.1212/WNL.0b013e3182a841a3. Epub 2013 Sep 27. 2013
9GRID2, SCAR18
A homozygous deletion in GRID2 causes a human phenotype with cerebellar ataxia and atrophy.
Utine GE, Haliloğlu G, Salanci B, Çetinkaya A, Kiper PÖ, Alanay Y, Aktas D, Boduroğlu K, Alikaşifoğlu M.
J Child Neurol 28(7):926-32. doi: 10.1177/0883073813484967. Epub 2013 Apr 22. 2013
10GRID2, GRM1
Glutamate receptor δ2 associates with metabotropic glutamate receptor 1 (mGluR1), protein kinase Cγ, and canonical transient receptor potential 3 and regulates mGluR1-mediated synaptic transmission in cerebellar Purkinje neurons.
Kato AS, Knierman MD, Siuda ER, Isaac JT, Nisenbaum ES, Bredt DS.
J Neurosci 32(44):15296-308. doi: 10.1523/JNEUROSCI.0705-12.2012. 2012
11CBLN1, CBLN2, CBLN3, CBLN4, GRID2
Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons.
Joo JY, Lee SJ, Uemura T, Yoshida T, Yasumura M, Watanabe M, Mishina M.
Biochem Biophys Res Commun 406(4):627-32. Epub 2011 Feb 26. 2011
12GRID2
D-serine regulates cerebellar LTD and motor coordination through the δ2 glutamate receptor.
Kakegawa W, Miyoshi Y, Hamase K, Matsuda S, Matsuda K, Kohda K, Emi K, Motohashi J, Konno R, Zaitsu K, Yuzaki M.
Nat Neurosci 14(5):603-11. Epub 2011 Apr 3. 2011
13GRID2
Sensory neuropathy attributable to loss of Bcl-w.
Courchesne SL, Karch C, Pazyra-Murphy MF, Segal RA.
J Neurosci 31(5):1624-34. 2011
14CBLN1, GRID2
Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum.
Uemura T, Lee SJ, Yasumura M, Takeuchi T, Yoshida T, Ra M, Taguchi R, Sakimura K, Mishina M.
Cell 141(6):1068-79. Epub 2010 May 27. 2010
15GRID2
The N-terminal domain of GluD2 (GluRdelta2) recruits presynaptic terminals and regulates synaptogenesis in the cerebellum in vivo.
Kakegawa W, Miyazaki T, Kohda K, Matsuda K, Emi K, Motohashi J, Watanabe M, Yuzaki M.
J Neurosci 29(18):5738-48. 2009
16BCL2L2, GRID2
Mitochondrial morphogenesis, dendrite development, and synapse formation in cerebellum require both Bcl-w and the glutamate receptor delta2.
Liu QA, Shio H.
PLoS Genet 4(6):e1000097. 2008
17GRID2
Differential regulation of synaptic plasticity and cerebellar motor learning by the C-terminal PDZ-binding motif of GluRdelta2.
Kakegawa W, Miyazaki T, Emi K, Matsuda K, Kohda K, Motohashi J, Mishina M, Kawahara S, Watanabe M, Yuzaki M.
J Neurosci 28(6):1460-8. 2008
18BCL2L2, GRID2
Mitochondrial morphogenesis, dendrite development, and synapse formation in cerebellum require both Bcl-w and the glutamate receptor delta2.
Liu QA, Shio H.
PLoS Genet 4(6):e1000097. doi: 10.1371/journal.pgen.1000097. 2008
19GRID2
Regulation of long-term depression and climbing fiber territory by glutamate receptor delta2 at parallel fiber synapses through its C-terminal domain in cerebellar Purkinje cells.
Uemura T, Kakizawa S, Yamasaki M, Sakimura K, Watanabe M, Iino M, Mishina M.
J Neurosci 27(44):12096-108. 2007
20GRID2
The glutamate receptor delta 2 in relation to cerebellar development and plasticity.
Gounko NV, Gramsbergen A, van der Want JJ.
Neurosci Biobehav Rev 31(8):1095-100. Epub 2007 May 13. Review. 2007
21GRID2, GRID2IP
Binding of glutamate receptor delta2 to its scaffold protein, Delphilin, is regulated by PKA.
Sonoda T, Mochizuki C, Yamashita T, Watanabe-Kaneko K, Miyagi Y, Shigeri Y, Yazama F, Okuda K, Kawamoto S.
Biochem Biophys Res Commun 350(3):748-52. Epub 2006 Sep 28. 2006
22GRID2
A new motif necessary and sufficient for stable localization of the delta2 glutamate receptors at postsynaptic spines.
Matsuda S, Matsuda K, Yuzaki M.
J Biol Chem 281(25):17501-9. Epub 2006 Apr 24. 2006
23GRID2, GRID2IP
Characterization of the delta2 glutamate receptor-binding protein delphilin: Splicing variants with differential palmitoylation and an additional PDZ domain.
Matsuda K, Matsuda S, Gladding CM, Yuzaki M.
J Biol Chem 281(35):25577-87. Epub 2006 Jul 11. 2006
24GRID2
Control of synaptic connection by glutamate receptor delta2 in the adult cerebellum.
Takeuchi T, Miyazaki T, Watanabe M, Mori H, Sakimura K, Mishina M.
J Neurosci 25(8):2146-56. 2005
25GRID2, GRID2IP
Identification and characterization of a novel Delphilin variant with an alternative N-terminus.
Yamashita T, Miyagi Y, Ono M, Ito H, Watanabe K, Sonoda T, Tsuzuki K, Ozawa S, Aoki I, Okuda K, Mishina M, Kawamoto S.
Brain Res Mol Brain Res 141(1):83-94. Epub 2005 Sep 15. 2005
26ATOH1, SMARCAD1, GRID2
The human glutamate receptor delta2 gene (GRID2) maps to chromosome 4q22.
Hu W, Zuo J, De Jager PL, Heintz N.
Genomics 47(1):143-5. 1998
27GRID2
Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene.
Zuo J, De Jager PL, Takahashi KA, Jiang W, Linden DJ, Heintz N.
Nature 388(6644):769-73. 1997
28GRID2
Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells.
Araki K, Meguro H, Kushiya E, Takayama C, Inoue Y, Mishina M.
Biochem Biophys Res Commun 197(3):1267-76. 1993