Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

MTSS1

contributors: mct - updated : 05-09-2016

HGNC name	metastasis suppressor 1
HGNC id	20443

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   of PDIA3, LYAR, NOP14, NCALD and MTSS1 genes in the ovarian cancer with poor prognosis

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	independent predictor for tumor recurrence and overall survival in patients with cholangiocarcinoma
Therapy target
	System Type Disorder Pubmed cancer digestive oesophagus important target for cancer therapy in oesophageal squamous cell carcinoma

ANIMAL & CELL MODELS

	Mtss1-deficient mice displayed a severe urinary concentration defect caused by compromised integrity of kidney epithelia intercellular junctions, which led to bone abnormalities and end-stage renal failure
	Mim-deficient mice displayed altered glutamatergic synaptic transmission and compatible behavioral defects