Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
| germinal mutation
|
|
|
|
in sporadic neural tube defects | tumoral
|
|
| --over
|
|
in colon cancer with invasive phenotype | tumoral
|
|
| --over
|
|
in mesenchymal tumours | constitutional
|
|
| --low
|
|
highly and transitory up-regulated during the partial-epithelial-mesenchymal transition EMT phase of tubulogenesis | tumoral
|
|
| --over
|
|
increased glioblastoma cell proliferation and invasion and promoted angiogenesis and glioblastoma growth | |