Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --low
|  
|
through promoter hypermethylation in gastric cancer | constitutional
|  
| deletion
|  
|  
|
of ZIC1 and ZIC4 in patient presented with mental retardation, epilepsy, and multiple congenital malformations including spina bifida, mild dysmorphic facial features and Dandy-Walker malformation ( | tumoral
|  
|  
| --over
|  
|
in all five subtypes of liposarcoma compared with normal fat | tumoral
|  
|  
| --low
|  
|
by hypermethylation may lead to promoter silencing of ZIC1 mRNA and associated with poor survival in hepatocellular carcinoma | |