Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | GABRE | contributors: - updated : 11-02-2004 |
HGNC name | gamma-aminobutyric acid (GABA) A receptor, epsilon |
HGNC id | 4085 |
|
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | component of a cluster |
text | clustered with GABRA3, GABRB4 and GABRQ |
STRUCTURE | 21.00 kb 9 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | status | provisional |
Map | see GABRA3 |
RNA |
TRANSCRIPTS | type | messenger |
---|
|
EXPRESSION |
Type |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
physiological period | pregnancy |
Text | placenta |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| a ligand binding site in the N terminal region, four transmembrane segments,one of which forming the wall of the channel and a large intracellular loop |
mono polymer | pentamer |
HOMOLOGY |
interspecies | homolog to murine Gabre |
Homologene |
FAMILY | ligand gated ionic channel family |
CATEGORY | receptor membrane ligand ion channel |
SUBCELLULAR LOCALIZATION |
basic FUNCTION | multisubunit chloride channel mediating the fastest inhibitory synaptic transmission in the central nervous system. |