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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

HOXB8

contributors: mct - updated : 17-04-2020

HGNC name	homeo box B8
HGNC id	5119

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Hoxb8 knocked-out mice exhibit an excessive pathologic grooming behavior, that is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania
	adult mice with an Lmx1b loss restricted to Hoxb8 neurons have nociception defects and disrupted organization of primary sensory afferent axons innervating the dorsal horn