Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

CASP10

contributors: mct - updated : 18-04-2015

HGNC name	caspase 10, apoptosis-related cysteine protease
HGNC id	1500

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

ALPS2

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in term placentas from women with pregnancies complicated by preeclampsia tumoral somatic mutation       CASP10 mutation might contribute to the pathogenesis of some colon carcinomas together with other CASP gene mutations (CASP3, CASP7, CASP8) tumoral somatic mutation       CASP10 mutation might contribute to the pathogenesis of factions of T-ALL and multiple myelomas

Susceptibility

to breast cancer

Variant & Polymorphism other	polymorphisms significantly associated with a highly decreased familial breast cancer risk

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS