Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CASP10 | contributors: mct - updated : 18-04-2015 |
HGNC name | caspase 10, apoptosis-related cysteine protease |
HGNC id | 1500 |
|
EXPRESSION |
Type |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
|
cell lineage
cell lines
| chronic myelogenous leukemia cell lines | fluid/secretion
| |
at STAGE |
physiological period | fetal, pregnancy |
Text | lung |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
|
mono polymer | heteromer , dimer |
isoforms | Precursor |
HOMOLOGY |
interspecies | homolog to C.elegans Ced-3 |
Homologene |
FAMILY | peptidase C14 family |
CATEGORY | enzyme |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
text |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
cell & other |
REGULATION |
activated by | CASP9 |
CASP8 which cleaved caspase-10 directly |
ASSOCIATED DISORDERS |
corresponding disease(s) | ALPS2 |
Susceptibility |
|
Variant & Polymorphism other | polymorphisms significantly associated with a highly decreased familial breast cancer risk |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |