Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

GPR25

contributors: mct - updated : 30-04-2020

HGNC name	G protein-coupled receptor 25
HGNC id	4480

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

seven transmembrane segments (7TM) receptor

HOMOLOGY

intraspecies

homolog to receptors involved in blood pressure regulation

Homologene

FAMILY

G protein coupled receptor 1 family

CATEGORY

receptor G

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

is an orphan G protein-coupled receptor in vertebrates, that has been implicated to be associated with autoimmune diseases and regulate blood pressure

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

orphan receptor GPR25 possesses two potential ligands APLN and APELA and its activation decreases intracellular cAMP levels in non-mammalian vertebrates, but also facilitates to unravel the physiological roles of GPR25 signaling in vertebrates

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS