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FLASH GENE
Symbol GPR25 contributors: mct - updated : 30-04-2020
HGNC name G protein-coupled receptor 25
HGNC id 4480
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivestomach    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane segments (7TM) receptor
HOMOLOGY
intraspecies homolog to receptors involved in blood pressure regulation
Homologene
FAMILY G protein coupled receptor 1 family
CATEGORY receptor G
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • is an orphan G protein-coupled receptor in vertebrates, that has been implicated to be associated with autoimmune diseases and regulate blood pressure
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • orphan receptor GPR25 possesses two potential ligands APLN and APELA and its activation decreases intracellular cAMP levels in non-mammalian vertebrates, but also facilitates to unravel the physiological roles of GPR25 signaling in vertebrates
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS