Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TNNI2 | contributors: mct/npt/pgu - updated : 28-12-2016 |
HGNC name | troponin I type 2 (skeletal, fast) |
HGNC id | 11946 |
|
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | arranged in tandem |
text | organized in pair with TNNT3 |
STRUCTURE | 2.01 kb 7 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
regulatory sequence
text structure
| putative regulatory element in the 5'region and a region containing MEF2, E-box, CCAC and CAGG element | |
MAPPING | cloned | Y | linked | N | status | confirmed |
Map | pter - TNNI2 - D11S922 - D11S932 - D11S1350 - cen |
regionally located | tightly linked to TNNT2 and ELF3 |
RNA |
TRANSCRIPTS | type | messenger |
---|
|
EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
HOMOLOGY |
interspecies | ortholog to murine Tnni2 |
homolog to C.elegans W03F8.1 |
intraspecies | homolog to TNNI1 |
homolog to TNNI3 |
Homologene |
FAMILY |
CATEGORY | motor/contractile , regulatory , structural protein |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytoskeleton |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | |
|
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | AMCD2B |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |