basic FUNCTION
| inhibitor of the cytolytic action of the terminal complement cascade growth hormone-dependent serum factor with protease-inhibiting activity |
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modulating SHH response in central nervous system |
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VTN and SERPINE1 are proteins that interact in the circulatory system and pericellular region to regulate fibrinolysis, cell adhesion, and migration |
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beneficial effect of VTN on oligodendrocytic differentiation of human embryonic stem cells (hESCs) |
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is a multi-functional protein found predominantly as a monomer in blood and as an oligomer in the extracellular matrix |
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is a glycoprotein found in normal serum and pathological extracellular matrix |
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inhibits neutrophil apoptosis through activation of integrin-associated signaling pathways |
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plays a previously unrecognized role in regulating endothelial permeability via conformational- and integrin-dependent effects on CDH5 trafficking |
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is involved in the whole process of atherosclerosis |
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may be involved in the pathogenesis of early-onset severe preeclampsia (EOSP), by inducing an imbalance between coagulation and fibrinolysis |
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importance of VTN and its interaction with the PLAUR in tumor growth |
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inhibits efferocytosis through interactions with apoptotic cells as well as with macrophages |
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adhesion to VTN allows likely for the uncoupling of FBN1 fibril formation from downstream signaling events by reducing ITGB1/ITGA5 integrin activation and FBN1 fibril extension |
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importance of VTN in the regulation of angiogenesis induced by VEGFA |
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plays a significant role in the malignant growth of tumor |
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Dental Bud Stem Cells (DBSCs) differentiation toward osteoblastic lineage was enhanced when cells were grown on fibronectin (FN1), vitronectin (VTN), and osteopontin (SPP1) |
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promotes the progress of the initial differentiation stage of cerebellar granule cell precursors (CGCPs) |