basic FUNCTION
| playing a role in protection of the lysosomal membrane from autodigestion and maintenance of the acidic environment of the lysosome |
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has established roles in adhesion and cellular homeostasis, including autophagocytosis and antigen presentation |
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LAMP1 and LAMP2 are delivered to phagosomes during the maturation process  |
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participates in chaperone-mediated autophagy, lysosome biogenesis, lysosome-autophagosome fusion, and lysosome locomotion along microtubule tracts toward phagosomes |
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may be involved the pathogenesis of accessory AV connections  |
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may participate in chaperone-mediated autophagy.Autophagy regulates T-lymphocyte homeostasis by promoting both survival and proliferation  |
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WDFY1 and LAMP2 can likely influence MTORC1 activity and regulate autophagy  |
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LAMP1 and LAMP2 have distinct functions, and the presence of both proteins together is required for the essential regulation of autophagy to avoid embryonic lethality  |
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plays a critical role in lysosomal biogenesis and maturation of autophagosomes/phagosomes  |