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FLASH GENE
Symbol CAPZA2 contributors: mct - updated : 15-03-2008
HGNC name capping protein (actin filament) muscle Z-line, alpha 2
HGNC id 1490
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer heteromer , dimer
HOMOLOGY
interspecies homolog to murine Caz2
Homologene
FAMILY F-actin capping protein alpha subunit family
CATEGORY structural protein
SUBCELLULAR LOCALIZATION
basic FUNCTION F-actin-capping protein that bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments,
thereby blocking the exchange of subunits at these ends
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component heterodimer of an alpha and a beta subunit
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS