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FLASH GENE
Symbol NUDT1 contributors: mct - updated : 26-06-2017
HGNC name nudix (nucleoside diphosphate linked moiety X)-type motif 1
HGNC id 8048
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional       loss of function
might be a causative factor for aging and age-related disorders
Susceptibility to diabetes type 1
Variant & Polymorphism other
  • Met allele at codon 83 might be involved in the development of type 1 diabetes mellitus
  • Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    cancer  
    NUDT1 inhibition may offer a general approach to treat cancers characterized by deregulated hypoxia signaling or redox imbalance
    ANIMAL & CELL MODELS