| basic FUNCTION
| major receptor that internalizes oxidized LDL |
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playing a role in platelet-collagen adhesion and in the transport and/or the regulation of fatty acid transport |
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acting as a facilitator or co-receptor for di-acylglyceride recognition through the TLR2/6 complex |
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playing an important role in proximal absorption of dietary fatty acid and cholesterol for optimal chylomicron formation, whereas CD36-independent mechanisms predominate in distal segments |
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CD36-mediated fatty acid oxidation is an important determinant for aerobic exercise capacity |
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major contributor to the macrophage uptake of lipoproteins modified by various oxidative pathways and subsequently to foam cell formation |
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may mediate albumin-induced cellular fibrosis since CD36 siRNA appeared to have anti-fibrosis effects  |
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may have important functions as a cell adhesion molecule |
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directly mediates cyto-adherence of plasmodium falciparum parasitized erythrocytes |
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may function in the transport and/or as a regulator of fatty acids transport |
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selective and non redundant sensor of microbial diacylglycerides that signal through the TLR2/6 heterodimer |
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may be responsible for the internalization of FSTL1 |
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novel serum amyloid A (SAA) receptor mediating SAA proinflammatory activity |
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involved in the vascular oxidative stress and neurovascular dysfunction induced by APP |
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participation of CD36 in membrane calcium influx in response to ER stress or purinergic receptor stimulation resulting in arachidonic acid liberation for PGE2 (prostaglandin E2) formation |
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participates in the phosphorylation and translocation of PLA2G4A to membranes to release arachidonic acid from phospholipids |
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located on the outer mitochondrial membrane, upstream of long-chain acyl-CoA synthetase, and regulates palmitate oxidation |
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diffusion of CD36 in the membrane of macrophages is regulated by interactions between CD36 and the cytoskeleton |
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CD36 and MSR1 involved in the development and/or progression of Acute Coronary Syndromes (ACS) |
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involved in the cytokine-induced fusion of macrophage |
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plays an important role in cell fusion during myogenic differentiation |
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promotes potentially vascular amyloid deposition and the resulting cerebrovascular damage, leading to neurovascular dysfunction and cognitive deficits |
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implicated in the mechanisms of vascular amyloid deposition |
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is involved in key upstream events leading to cerebral amyloid angiopathy (CAA) and to the associated vascular damage and neurovascular dysfunction |
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involvement of CD36 in monocyte activation by antiphospholipid antibodies |
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is likely central to fatty acid (FA) uptake via its effects on intracellular metabolism |
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plays a central role in lipid metabolism by promoting macrophage cholesterol efflux with the potential to reduce atherosclerotic lesions |
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is a novel regulator of HMG-CoA reductase function and INSIG-1/2 expression, 2 critical steps regulating cholesterol synthesis in hepatocytes |
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essential cell surface and skeletal muscle outer mitochondrial membrane glycoprotein involved in multiple functions in the body |
