| 1 | CD36, FCER1G, RAP1B, RRAS2
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| TC21/RRas2 regulates glycoprotein VI-FcRγ-mediated platelet activation and thrombus stability.
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| Janapati S, Wurtzel J, Dangelmaier C, Manne BK, Bhavanasi D, Kostyak JC, Kim S, Holinstat M, Kunapuli SP, Goldfinger LE.
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| J Thromb Haemost Thromb Haemost. 2018 Jun 8. doi: 10.1111/jth.14197. [Epub ahead of print]
2018
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| 2 | CD36, CUL7, IRS1
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| Ubiquitinated CD36 sustains insulin-stimulated Akt activation by stabilizing insulin receptor substrate 1 in myotubes.
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| Sun S, Tan P, Huang X, Zhang W, Kong C, Ren F, Su X.
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| J Biol Chem 293(7):2383-2394. doi: 10.1074/jbc.M117.811471. Epub 2017 Dec 21.
2018
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| 3 | CD36, PPARG, TCF4, WNT1
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| Wnt1 positively regulates CD36 expression via TCF4 and PPAR-γ in macrophages.
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| Wang S, Sun Z, Zhang X, Li Z, Wu M, Zhao W, Wang H, Chen T, Yan H, Zhu J.
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| Cell Physiol Biochem 35(4):1289-302. doi: 10.1159/000373951.
2015
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| 4 | CD36, CD5L
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| The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses.
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| Sanjurjo L, Amézaga N, Aran G, Naranjo-Gómez M, Arias L, Armengol C, Borràs FE, Sarrias MR.
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| Autophagy 11(3):487-502. doi: 10.1080/15548627.2015.1017183.
2015
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| 5 | CD36, THBS1
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| Supporting roles of platelet thrombospondin-1 and CD36 in thrombus formation on collagen.
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| Kuijpers MJ, de Witt S, Nergiz-Unal R, van Kruchten R, Korporaal SJ, Verhamme P, Febbraio M, Tjwa M, Voshol PJ, Hoylaerts MF, Cosemans JM, Heemskerk JW.
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| Arterioscler Thromb Vasc Biol 34(6):1187-92. doi: 10.1161/ATVBAHA.113.302917. Epub 2014 Mar 27.
2014
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| 6 | CD36
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| Scavenger receptor CD36 mediates inhibition of cholesterol synthesis via activation of the PPARγ/PGC-1α pathway and Insig1/2 expression in hepatocytes.
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| Rodrigue-Way A, Caron V, Bilodeau S, Keil S, Hassan M, Lévy E, Mitchell GA, Tremblay A.
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| FASEB J 28(4):1910-23. doi: 10.1096/fj.13-240168. Epub 2013 Dec 26.
2014
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| 7 | CD36, KLF2
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| Krüppel-like factor 2 promotes liver steatosis through upregulation of CD36.
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| Chen JL, Lu XJ, Zou KL, Ye K.
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| J Lipid Res 55(1):32-40. doi: 10.1194/jlr.M039453. Epub 2013 Jul 15.
2014
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| 8 | CD36
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| Innate immunity receptor CD36 promotes cerebral amyloid angiopathy.
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| Park L, Zhou J, Zhou P, Pistick R, El Jamal S, Younkin L, Pierce J, Arreguin A, Anrather J, Younkin SG, Carlson GA, McEwen BS, Iadecola C.
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| Proc Natl Acad Sci U S A 110(8):3089-94. doi: 10.1073/pnas.1300021110. Epub 2013 Feb 4.
2013
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| 9 | CD36
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| CD36 enhances fatty acid uptake by increasing the rate of intracellular esterification but not transport across the plasma membrane.
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| Xu S, Jay A, Brunaldi K, Huang N, Hamilton JA.
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| Biochemistry 52(41):7254-61. doi: 10.1021/bi400914c. Epub 2013 Oct 3.
2013
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| 10 | CD36
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| The involvement of CD36 in monocyte activation by antiphospholipid antibodies.
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| Kato M, Atsumi T, Oku K, Amengual O, Nakagawa H, Fujieda Y, Otomo K, Horita T, Yasuda S, Koike T.
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| Lupus 22(8):761-71. doi: 10.1177/0961203313490242.
2013
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| 11 | CD36, MSR1, OLR1
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| Regulation of MSR-1 and CD36 in macrophages by LOX-1 mediated through PPAR-γ.
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| Dai Y, Su W, Ding Z, Wang X, Mercanti F, Chen M, Raina S, Mehta JL.
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| Biochem Biophys Res Commun 431(3):496-500. doi: 10.1016/j.bbrc.2013.01.029. Epub 2013 Jan 16.
2013
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| 12 | CD36, PTAFR
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| Clearance of apoptotic cells by macrophages induces regulatory phenotype and involves stimulation of CD36 and platelet-activating factor receptor.
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| Ferracini M, Rios FJ, Pecenin M, Jancar S.
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| Mediators Inflamm 2013:950273. doi: 10.1155/2013/950273.
2013
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| 13 | CD36
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| Comparative Studies of Vertebrate Platelet Glycoprotein 4 (CD36).
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| Holmes RS.
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| Biomolecules 2(3):389-414. doi: 10.3390/biom2030389.
2012
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| 14 | CD36
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| Functional consequences of CD36 downregulation by TLR signals.
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| Zamora C, Cantó E, Nieto JC, Angels Ortiz M, Juarez C, Vidal S.
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| Cytokine 60(1):257-65. doi: 10.1016/j.cyto.2012.06.020. Epub 2012 Jul 12.
2012
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| 15 | CD36
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| CD36 ectodomain phosphorylation blocks thrombospondin-1 binding: structure-function relationships and regulation by protein kinase C.
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| Chu LY, Silverstein RL.
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| Arterioscler Thromb Vasc Biol 32(3):760-7. doi: 10.1161/ATVBAHA.111.242511. Epub 2012 Jan 12.
2012
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| 16 | CD36, MSR1
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| Highly upregulated expression of CD36 and MSR1 in circulating monocytes of patients with acute coronary syndromes.
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| Piechota M, Banaszewska A, Dudziak J, Slomczynski M, Plewa R.
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| Protein J 31(6):511-8. doi: 10.1007/s10930-012-9431-8.
2012
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| 17 | CD36, SLC2A4, VAMP3
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| Overexpression of vesicle-associated membrane protein (VAMP) 3, but not VAMP2, protects glucose transporter (GLUT) 4 protein translocation in an in vitro model of cardiac insulin resistance.
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| Schwenk RW, Angin Y, Steinbusch LK, Dirkx E, Hoebers N, Coumans WA, Bonen A, Broers JL, van Eys GJ, Glatz JF, Luiken JJ.
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| J Biol Chem 287(44):37530-9. doi: 10.1074/jbc.M112.363630. Epub 2012 Aug 30.
2012
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| 18 | CD36
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| CD36 is required for myoblast fusion during myogenic differentiation.
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| Park SY, Yun Y, Kim IS.
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| Biochem Biophys Res Commun 427(4):705-10. doi: 10.1016/j.bbrc.2012.09.119. Epub 2012 Oct 1.
2012
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| 19 | APP, CD36
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| Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta.
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| Park L, Wang G, Zhou P, Zhou J, Pitstick R, Previti ML, Younkin L, Younkin SG, Van Nostrand WE, Cho S, Anrather J, Carlson GA, Iadecola C.
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| Proc Natl Acad Sci U S A 108(12):5063-8. Epub 2011 Mar 7.
2011
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| 20 | CD36
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| CD36 protein is involved in store-operated calcium flux, phospholipase A2 activation, and production of prostaglandin E2.
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| Kuda O, Jenkins CM, Skinner JR, Moon SH, Su X, Gross RW, Abumrad NA.
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| J Biol Chem 286(20):17785-95. Epub 2011 Mar 31.
2011
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| 21 | CD36
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| FAT/CD36 is located on the outer mitochondrial membrane, upstream of long-chain acyl-CoA synthetase, and regulates palmitate oxidation.
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| Smith BK, Jain SS, Rimbaud S, Dam A, Quadrilatero J, Ventura-Clapier R, Bonen A, Holloway GP.
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| Biochem J 437(1):125-34.
2011
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| 22 | CD36
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| Cytoskeletal control of CD36 diffusion promotes its receptor and signaling function.
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| Jaqaman K, Kuwata H, Touret N, Collins R, Trimble WS, Danuser G, Grinstein S.
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| Cell 146(4):593-606.
2011
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| 23 | CD36
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| Variants of the CD36 gene and metabolic syndrome in Boston Puerto Rican adults.
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| Noel SE, Lai CQ, Mattei J, Parnell LD, Ordovas JM, Tucker KL.
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| Atherosclerosis 211(1):210-5. Epub 2010 Feb 18.
2010
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| 24 | CD36
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| The Toll-like receptor 2 (TLR2) ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR2.
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| Shamsul HM, Hasebe A, Iyori M, Ohtani M, Kiura K, Zhang D, Totsuka Y, Shibata K.
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| Immunology 130(2):262-72. Epub 2010 Jan 27.
2010
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| 25 | CD36
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| Soluble CD36 (sCD36) clusters with markers of insulin resistance, and high sCD36 is associated with increased type 2 diabetes risk.
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| Handberg A, Norberg M, Stenlund H, Hallmans G, Attermann J, Eriksson JW.
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| J Clin Endocrinol Metab 95(4):1939-46. Epub 2010 Feb 5.
2010
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| 26 | CD36
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| CD36 is a novel serum amyloid A (SAA) receptor mediating SAA binding and SAA-induced signaling in human and rodent cells.
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| Baranova IN, Bocharov AV, Vishnyakova TG, Kurlander R, Chen Z, Fu D, Arias IM, Csako G, Patterson AP, Eggerman TL.
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| J Biol Chem 285(11):8492-506. Epub 2010 Jan 14.
2010
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| 27 | CD36
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| CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.
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| Stewart CR, Stuart LM, Wilkinson K, van Gils JM, Deng J, Halle A, Rayner KJ, Boyer L, Zhong R, Frazier WA, Lacy-Hulbert A, El Khoury J, Golenbock DT, Moore KJ.
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| Nat Immunol 11(2):155-61. Epub 2009 Dec 27.
2010
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| 28 | CD36
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| The Human Scavenger Receptor CD36: glycosylation status and its role in trafficking and function.
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| Hoosdally SJ, Andress EJ, Wooding C, Martin CA, Linton KJ.
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| J Biol Chem 284(24):16277-88. Epub 2009 Apr 15.
2009
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| 29 | CD36
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| Receptor of advanced glycation end products (RAGE) positively regulates CD36 expression and reactive oxygen species production in human monocytes in diabetes.
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| Xanthis A, Hatzitolios A, Fidani S, Befani C, Giannakoulas G, Koliakos G.
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| Angiology 60(6):772-9. Epub 2009 Feb 3.
2009
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| 30 | CD36
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| CD36 and TLR interactions in inflammation and phagocytosis: implications for malaria.
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| Erdman LK, Cosio G, Helmers AJ, Gowda DC, Grinstein S, Kain KC.
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| J Immunol 183(10):6452-9. Epub 2009 Oct 28.
2009
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| 31 | CD36
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| Mapping and characterization of the binding site for specific oxidized phospholipids and oxidized low density lipoprotein of scavenger receptor CD36.
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| Kar NS, Ashraf MZ, Valiyaveettil M, Podrez EA.
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| J Biol Chem 283(13):8765-71. Epub 2008 Feb 1. 2008
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| 32 | CD36, CD36D
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| Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol.
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| Love-Gregory L, Sherva R, Sun L, Wasson J, Schappe T, Doria A, Rao DC, Hunt SC, Klein S, Neuman RJ, Permutt MA, Abumrad NA.
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| Hum Mol Genet 17(11):1695-704. Epub 2008 Feb 27. 2008
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| 33 | CD36, CD36D
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| Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension.
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| Pravenec M, Churchill PC, Churchill MC, Viklicky O, Kazdova L, Aitman TJ, Petretto E, Hubner N, Wallace CA, Zimdahl H, Zidek V, Landa V, Dunbar J, Bidani A, Griffin K, Qi N, Maxova M, Kren V, Mlejnek P, Wang J, Kurtz TW.
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| Nat Genet 40(8):952-4. Epub 2008 Jun 29. 2008
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| 34 | CD36, HSPA4
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| CD36 signaling inhibits the translation of heat shock protein 70 induced by oxidized low density lipoprotein through activation of peroxisome proliferators-activated receptor gamma.
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| Lee KJ, Ha ES, Kim MK, Lee SH, Suh JS, Lee SH, Park KH, Park JH, Kim DJ, Kang D, Kim BC, Jeoung D, Kim YK, Kim HD, Hahn JH.
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| Exp Mol Med 40(6):658-68.
2008
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| 35 | CD36, NFE2L2
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| Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements.
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| Maruyama A, Tsukamoto S, Nishikawa K, Yoshida A, Harada N, Motojima K, Ishii T, Nakane A, Yamamoto M, Itoh K.
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| Arch Biochem Biophys 477(1):139-45. Epub 2008 Jun 15.
2008
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| 36 | CD36, CD36D
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| CD36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine.
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| Nassir F, Wilson B, Han X, Gross RW, Abumrad NA.
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| J Biol Chem 282(27):19493-501. Epub 2007 May 15. 2007
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| 37 | CD36, CD36D
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| Attenuated aerobic exercise capacity in CD36 deficiency.
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| Yanai H, Watanabe I, Ishii K, Morimoto M, Fujiwara H, Yoshida S, Hui SP, Matsuno K, Chiba H.
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| J Med Genet 44(7):445-7. Epub 2007 Apr 5. 2007
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| 38 | CD36, CD36D
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| CD36 is a receptor for oxidized high density lipoprotein: implications for the development of atherosclerosis.
|
| Thorne RF, Mhaidat NM, Ralston KJ, Burns GF.
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| FEBS Lett 581(6):1227-32. Epub 2007 Feb 28. 2007
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| 39 | CD36, CD36D
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| Importance of the carboxyl terminus of FAT/CD36 for plasma membrane localization and function in long-chain fatty acid uptake.
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| Eyre NS, Cleland LG, Tandon NN, Mayrhofer G.
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| J Lipid Res 48(3):528-42. Epub 2006 Dec 1. 2007
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| 40 | CD36, CD36D
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| CD36 deficiency rescues lipotoxic cardiomyopathy.
|
| Yang J, Sambandam N, Han X, Gross RW, Courtois M, Kovacs A, Febbraio M, Finck BN, Kelly DP.
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| Circ Res 100(8):1208-17. Epub 2007 Mar 15. 2007
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| 41 | CD36
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| CD36 is a novel and potential anti-fibrogenic target in albumin-induced renal proximal tubule fibrosis.
|
| Yang YL, Lin SH, Chuang LY, Guh JY, Liao TN, Lee TC, Chang WT, Chang FR, Hung MY, Chiang TA, Hung CY.
|
| J Cell Biochem 101(3):735-44.
2007
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| 42 | CD36
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| Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype.
|
| Podrez EA, Byzova TV, Febbraio M, Salomon RG, Ma Y, Valiyaveettil M, Poliakov E, Sun M, Finton PJ, Curtis BR, Chen J, Zhang R, Silverstein RL, Hazen SL.
|
| Nat Med 13(9):1086-95. Epub 2007 Aug 26.PMID: 17721545 2007
|
| 43 | PWS, CD36
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| CD36 expression and its relationship with obesity in blood cells from people with and without Prader-Willi syndrome.
|
| Webb T, Whittington J, Holland AJ, Soni S, Boer H, Clarke D, Horsthemke B.
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| Clin Genet 69(1):26-32. 2006
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| 44 | CD36
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| Identification of the oxidized low-density lipoprotein scavenger receptor CD36 in plasma: a novel marker of insulin resistance.
|
| Handberg A, Levin K, Hojlund K, Beck-Nielsen H.
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| Circulation 114(11):1169-76. Epub 2006 Sep 4. 2006
|
| 45 | CD36
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| Cholesteryl ester hydroperoxides increase macrophage CD36 gene expression via PPARalpha.
|
| Jedidi I, Couturier M, Therond P, Gardes-Albert M, Legrand A, Barouki R, Bonnefont-Rousselot D, Aggerbeck M.
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| Biochem Biophys Res Commun 351(3):733-8. Epub 2006 Nov 3. 2006
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| 46 | CD36
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| CD36 is important for chylomicron formation and secretion and may mediate cholesterol uptake in the proximal intestine.
|
| Nauli AM, Nassir F, Zheng S, Yang Q, Lo CM, Vonlehmden SB, Lee D, Jandacek RJ, Abumrad NA, Tso P.
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| Gastroenterology 131(4):1197-207. Epub 2006 Aug 16.
2006
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| 47 | CD36
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| CD36 is a sensor of diacylglycerides.
|
| Hoebe K, Georgel P, Rutschmann S, Du X, Mudd S, Crozat K, Sovath S, Shamel L, Hartung T, Zahringer U, Beutler B.
|
| Nature 433(7025):523-7. 2005
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| 48 | CD36, SLC27A1
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| The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR.
|
| Chabowski A, Coort SL, Calles-Escandon J, Tandon NN, Glatz JF, Luiken JJ, Bonen A.
|
| FEBS Lett 579(11):2428-32. 2005
|
| 49 | SLC27A1, CD36
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| Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells.
|
| Garcia-Martinez C, Marotta M, Moore-Carrasco R, Guitart M, Camps M, Busquets S, Montell E, Gomez-Foix AM.
|
| Am J Physiol Cell Physiol 288(6):C1264-72. 2005
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| 50 | SLC26A2, ACG1B, ATSG2, DTD, EDM4, CD36
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| Functional expression and cellular distribution of diastrophic dysplasia sulfate transporter (DTDST) gene mutations in HEK cells.
|
| Karniski LP.
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| Hum Mol Genet 13(19):2165-71. Epub 2004 Aug 04. 2004
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| 51 | CD36
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| CD36 polymorphism is associated with protection from cerebral malaria
|
| Omi K, Ohashi J, Patarapotikul J, Hananantachai H, Naka I, Looareesuwan S, Tokunaga K.
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| Am J Hum Genet 72(2):364-74. 2003
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| 52 | CD36, CD36D
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| Molecular basis of the Cd36 chromosomal deletion underlying SHR defects in insulin action and fatty acid metabolism.
|
| Glazier AM, Scott J, Aitman TJ.
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| Mamm Genome 13(2):108-13. 2002
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| 53 | CD36, CD36D
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| Analyses of genetic abnormalities in type I CD36 deficiency in Japan: identification and cell biological characterization of two novel mutations that cause CD36 deficiency in man.
|
| Kashiwagi H, Tomiyama Y, Nozaki S, Kiyoi T, Tadokoro S, Matsumoto K, Honda S, Kosugi S, Kurata Y, Matsuzawa Y.
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| Hum Genet 108(6):459-66. 2001
|
| 54 | CD36
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| A link between diabetes and atherosclerosis: Glucose regulates expression of CD36 at the level of translation.
|
| Griffin E, Re A, Hamel N, Fu C, Bush H, McCaffrey T, Asch AS.
|
| Nat Med 7(7):840-6.PMID: 11433350 2001
|
| 55 | CD36
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| Malaria susceptibility and CD36 mutation.
|
| Aitman TJ, Cooper LD, Norsworthy PJ, Wahid FN, Gray JK, Curtis BR, McKeigue PM, Kwiatkowski D, Greenwood BM, Snow RW, Hill AV, Scott J.
|
| Nature 405(6790):1015-6. No abstract available. 2000
|
| 56 | ADRA2A, ADRB1, AGTR1, CAFG, CD36, CETP, CSF1, CSF2, CYP11B2, ECE1, EDN1, EDNRA, EDNRB, EGR1, F2R, FGA, FGB, FHBL1, HGF, ICAM1, IGF1, IL1A, IL6, LPA, MGP, MSR1, MTTP, NOS2, NOS3, PDGFA, PDGFRA, SELP, TGFB1, TNF, VCAM1, VDR
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| Sequence diversity in 36 candidate genes for cardiovascular disorders.
|
| Cambien F, Poirier O, Nicaud V, Herrmann SM, Mallet C, Ricard S, Behague I, Hallet V, Blanc H, Loukaci V, Thillet J, Evans A, Ruidavets JB, Arveiler D, Luc G, Tiret L.
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| Am J Hum Genet 65(1):183-91. 1999
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| 57 | CD36, SCARB1, SCARB2
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| The CD36, CLA-1 (CD36L1), and LIMPII (CD36L2) gene family : cellular distribution, chromosomal location, and genetic evolution.
|
| Calvo D, et al.
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| Genomics 25 : 100-106. 1995
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| 58 | CD36, CD36D
|
| Molecular basis of CD36 deficiency. Evidence that a 478C-T substitution (proline90-serine) in CD36 cDNA accounts for CD36 deficiency.
|
| Kashiwagi H, et al.
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| J Clin Invest 95 : 1040-1046. 1995
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| 59 | CD36
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| A dinucleotide repeat in the third intron of CD36.
|
| Lipsky RH, et al.
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| Hum Mol Genet 3 : 217. 1994
|
| 60 | CD36, CD36D
|
| Identification of molecular defects in a subject with type I CD36 deficiency.
|
| Kashiwagi H, et al.
|
| Blood 83 : 3545-3552. 1994
|
| 61 | CD36
|
| Structural organization of the gene for human CD36 glycoprotein.
|
| Armesilla AL, Vega MA.
|
| J Biol Chem 269(29):18985-91. 1994
|
| 62 | CD36
|
| Gene encoding the collagen type I and thrombospondin receptor CD36 is located on chromosome 7q11.2.
|
| Fernandez-Ruiz E, et al.
|
| Genomics 17 : 759-761. 1993
|
| 63 | CD36
|
| Characterization of two alternatively spliced 5'-untranslated exons of the human CD36 gene in different cell types.
|
| Taylor KT, Tang Y, Sobieski DA, Lipsky RH.
|
| Gene 133(2):205-12. 1993
|
| 64 | CD36
|
| Isolation and characterization of platelet glycoprotein IV (CD36).
|
| Tandon NN, Lipsky RH, Burgess WH, Jamieson GA.
|
| J Biol Chem 264(13):7570-5.PMID: 2468669 1989
|