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	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

HPGD

contributors: mct/npt - updated : 15-07-2008

HGNC name	hydroxyprostaglandin dehydrogenase 15-(NAD)
HGNC id	5154

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

PHTO , ICNC

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral       loss of function notably in colorectal cancer and non-small cell lung cancer

Susceptibility

Variant & Polymorphism

Candidate gene	HPGD mutation analysis and/or urinary PGE2 and PGE-M measurements may prove to be useful early investigations in patients with unexplained clubbing
Marker
Therapy target

corresponding disease(s)

PHTO , ICNC

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral       loss of function notably in colorectal cancer and non-small cell lung cancer

Susceptibility

Variant & Polymorphism

Candidate gene	HPGD mutation analysis and/or urinary PGE2 and PGE-M measurements may prove to be useful early investigations in patients with unexplained clubbing
Marker
Therapy target

ANIMAL & CELL MODELS