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References OMIM Gene GeneReviews HGMD HGNC
last update : 03-07-2009
Symbol ICNC
Location 4q34-q35
Name isolated congenital nail clubbing
Corresponding gene HPGD
Main clinical features
  • characterized by enlargement of the nail plate and terminal segments of the fingers and toes, resulting from proliferation of the connective tissues between the nail matrix and the distal phalanx
  • loss of the normal angle between the nail and the posterior nail fold
  • Genetic determination autosomal recessive
    Function/system disorder dermatology
    Type disease