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FLASH GENE

Symbol

PTPRM

contributors: - updated : 12-04-2006

HGNC name	protein tyrosine phosphatase, receptor type, M
HGNC id	9675

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine thyroid       highly Lymphoid/Immune thymus       highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective bone

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	an extracellular region
	a single transmembrane region
	and two tandem catalytic domains
	four 4 fibronectin type-III domains
	a Ig-like c2-type (immunoglobulin-like) domain
	a MAM domain
	two tyrosine-protein phosphatase domains

HOMOLOGY

Homologene

FAMILY

protein tyrosine phosphatase (PTP) family

CATEGORY

receptor membrane

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,cytoplasm
	intracellular,nucleus

basic FUNCTION

may play a key role in signal transduction and growth control

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS