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FLASH GENE
Symbol PTPRM contributors: - updated : 12-04-2006
HGNC name protein tyrosine phosphatase, receptor type, M
HGNC id 9675
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinethyroid   highly
Lymphoid/Immunethymus   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an extracellular region
  • a single transmembrane region
  • and two tandem catalytic domains
  • four 4 fibronectin type-III domains
  • a Ig-like c2-type (immunoglobulin-like) domain
  • a MAM domain
  • two tyrosine-protein phosphatase domains
  • HOMOLOGY
    Homologene
    FAMILY protein tyrosine phosphatase (PTP) family
    CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION may play a key role in signal transduction and growth control
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS