Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PLAUR | contributors: mct/npt/pgu - updated : 30-11-2016 |
HGNC name | plasminogen activator, urokinase receptor |
HGNC id | 9053 |
|
Location | 19q13.2 Physical location : 44.150.247 - 44.174.502 |
Synonym name | |
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Synonym symbol(s) | CD87, UPAR, URKR, MO3 |
DNA |
TYPE | functioning gene |
STRUCTURE | 24.25 kb 7 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence | Binding site |
MAPPING | cloned | Y | linked | Y | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type |
expressed in | (based on citations) |
organ(s) |
tissue |
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cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
| |
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HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | transcription factor , receptor membrane |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria | |
intracellular,cytoplasm,organelle,membrane | |
intracellular,nucleus |
basic FUNCTION | |
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| |
|
CELLULAR PROCESS | nucleotide, transcription |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | |
|
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
| |
| |
| |
|
cell & other |
REGULATION |
repressed by | FOXP2 (down-regulates both the SRPX2 and the PLAUR genes and this transcriptional regulation is lost when FOXP2 bears a pathogenic p.R553H mutation that is known to cause DVD (developmental verbal dyspraxia) |
Other | regulation of urokinase receptor expression by protein tyrosine phosphatases |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
|
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ANIMAL & CELL MODELS |