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| CD14-deficient miceare highly resistant to shock induced by either live Gram-negative bacteria or LPS and show dramatically reduced levels of bacteremia  | |
Bone marrow-derived macrophages (BMDMs) from CD14-/- mice exhibited impaired responses to polyinosine-polycytidylic acid (pIpC) and reduced production of inflammatory cytokines |
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mice lacking CD14 exhibited reduced insoluble, but not soluble, levels of betta-amyloid at 7 months of age and have a significant change in the inflammatory environment of the brain |