| 1 | CD14, LGALS4
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| Galectin-4 Interaction with CD14 Triggers the Differentiation of Monocytes into Macrophage-like Cells via the MAPK Signaling Pathway.
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| Hong SH, Shin JS, Chung H, Park CG.
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| Immune Netw 19(3):e17. doi: 10.4110/in.2019.19.e17. eCollection 2019 Jun.
2019
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| 2 | CD14
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| Presepsin as a diagnostic marker of sepsis in children and adolescents: a systemic review and meta-analysis.
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| Yoon SH, Kim EH, Kim HY, Ahn JG.
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| BMC Infect Dis 19(1):760. doi: 10.1186/s12879-019-4397-1.
2019
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| 3 | CD14
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| Decreased Expression of CD14 in MSU-Mediated Inflammation May Be Associated with Spontaneous Remission of Acute Gout.
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| Duan L, Luo J, Fu Q, Shang K, Wei Y, Wang Y, Li Y, Chen J.
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| J Immunol Res 2019:7143241. doi: 10.1155/2019/7143241. eCollection 2019.
2019
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| 4 | CD14
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| Association of plasma soluble CD14 level with asthma severity in adults: a case control study in China.
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| Zhou T, Huang X, Ma J, Zhou Y, Liu Y, Xiao L, Yuan J, Xie J, Chen W.
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| Respir Res 20(1):19. doi: 10.1186/s12931-019-0987-0.
2019
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| 5 | CD14
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| Macrophage CD14 impacts immune defenses against influenza virus in allergic hosts.
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| Palipane M, Snyder JD, LeMessurier KS, Schofield AK, Woolard SN, Samarasinghe AE.
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| Microb Pathog 127:212-219. doi: 10.1016/j.micpath.2018.12.008. Epub 2018 Dec 5.
2019
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| 6 | CD14
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| Comparison between presepsin and procalcitonin in early diagnosis of neonatal sepsis.
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| Iskandar A, Arthamin MZ, Indriana K, Anshory M, Hur M, Di Somma S; GREAT Network.
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| J Matern Fetal Neonatal Med 32(23):3903-3908. doi: 10.1080/14767058.2018.1475643. Epub 2018 May 27.
2019
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| 7 | CD14
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| Deficiency of the pattern-recognition receptor CD14 protects against joint pathology and functional decline in a murine model of osteoarthritis.
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| Sambamurthy N, Zhou C, Nguyen V, Smalley R, Hankenson KD, Dodge GR, Scanzello CR.
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| PLoS One 13(11):e0206217. doi: 10.1371/journal.pone.0206217. eCollection 2018.
2018
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| 8 | CD14
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| Increased presepsin levels are associated with the severity of fungal bloodstream infections.
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| Bamba Y, Moro H, Aoki N, Koizumi T, Ohshima Y, Watanabe S, Sakagami T, Koya T, Takada T, Kikuchi T.
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| PLoS One 13(10):e0206089. doi: 10.1371/journal.pone.0206089. eCollection 2018.
2018
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| 9 | CD14
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| Study on the correlation between CD14 gene polymorphism and susceptibility to laryngeal cancer.
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| Su J, Cui J, Xue HT, Tian JH, Zhang JH.
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| Eur Rev Med Pharmacol Sci 21(19):4292-4297.
2017
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| 10 | CD14
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| CD14 is a key mediator of both lysophosphatidic acid and lipopolysaccharide induction of foam cell formation.
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| An D, Hao F, Zhang F, Kong W, Chun J, Xu X, Cui MZ.
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| J Biol Chem 292(35):14391-14400. doi: 10.1074/jbc.M117.781807. Epub 2017 Jul 13.
2017
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| 11 | CD14
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| Presepsin for the detection of early-onset sepsis in preterm newborns.
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| Montaldo P, Rosso R, Santantonio A, Chello G, Giliberti P.
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| Pediatr Res 81(2):329-334. doi: 10.1038/pr.2016.217. Epub 2016 Nov 3.
2017
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| 12 | CD14
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| Plasmatic presepsin (sCD14-ST) concentrations in acute pyelonephritis in adult patients.
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| Claessens YE, Trabattoni E, Grabar S, Quinquis L, Der Sahakian G, Anselmo M, Schmidt J, de la Coussaye JE, Plaisance P, Casalino E, Potel G, Lecomte F, Borderie D, Chenevier-Gobeaux C.
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| Clin Chim Acta 464:182-188. doi: 10.1016/j.cca.2016.11.036. Epub 2016 Nov 24.
2017
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| 13 | CD14
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| Soluble CD14 inhibits contractile function and insulin action in primary adult rat cardiomyocytes.
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| Overhagen S, Blumensatt M, Fahlbusch P, Herzfeld de Wiza D, Müller H, Maxhera B, Akhyari P, Ouwens DM.
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| Biochim Biophys Acta Mol Basis Dis 1863(2):365-374. doi: 10.1016/j.bbadis.2016.11.002. Epub 2016 Nov 3.
2017
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| 14 | CD14
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| Genetic polymorphism in CD14 gene, a co-receptor of TLR4 associated with non-alcoholic fatty liver disease.
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| Kapil S, Duseja A, Sharma BK, Singla B, Chakraborti A, Das A, Ray P, Dhiman RK, Chawla Y.
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| World J Gastroenterol 22(42):9346-9355.
2016
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| 15 | CD14, IL17A, IL1B
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| New roles for CD14 and IL-β linking inflammatory dendritic cells to IL-17 production in memory CD4+ T cells.
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| Ilarregui JM, van Beelen AJ, Fehres CM, Bruijns SC, García-Vallejo JJ, van Kooyk Y.
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| Immunol Cell Biol 94(10):907-916. doi: 10.1038/icb.2016.66. Epub 2016 Aug 23.
2016
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| 16 | CD14, S100A9, TLR4
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| CD14 Is a Co-Receptor for TLR4 in the S100A9-Induced Pro-Inflammatory Response in Monocytes.
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| He Z, Riva M, Björk P, Swärd K, Mörgelin M, Leanderson T, Ivars F.
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| PLoS One 11(5):e0156377. doi: 10.1371/journal.pone.0156377. eCollection 2016.
2016
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| 17 | CD14
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| CD14 is associated with biliary stricture formation.
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| Friedrich K, Smit M, Brune M, Giese T, Rupp C, Wannhoff A, Kloeters P, Leopold Y, Denk GU, Weiss KH, Stremmel W, Sauer P, Hohenester S, Schirmacher P, Schemmer P, Gotthardt DN.
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| Hepatology 64(3):843-52. doi: 10.1002/hep.28543. Epub 2016 Apr 20.
2016
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| 18 | CD14
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| CD14 is a key organizer of microglial responses to CNS infection and injury.
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| Janova H, Böttcher C, Holtman IR, Regen T, van Rossum D, Götz A, Ernst AS, Fritsche C, Gertig U, Saiepour N, Gronke K, Wrzos C, Ribes S, Rolfes S, Weinstein J, Ehrenreich H, Pukrop T, Kopatz J, Stadelmann C, Salinas-Riester G, Weber MS, Prinz M, Brück W, Eggen BJ, Boddeke HW, Priller J, Hanisch UK.
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| Glia 64(4):635-49. doi: 10.1002/glia.22955. Epub 2015 Dec 18.
2016
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| 19 | CD14
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| Clinical impact of kidney function on presepsin levels.
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| Nagata T, Yasuda Y, Ando M, Abe T, Katsuno T, Kato S, Tsuboi N, Matsuo S, Maruyama S.
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| PLoS One 10(6):e0129159. doi: 10.1371/journal.pone.0129159. eCollection 2015.
2015
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| 20 | CD14
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| The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load.
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| Egge KH, Barratt-Due A, Nymo S, Lindstad JK, Pharo A, Lau C, Espevik T, Thorgersen EB, Mollnes TE.
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| Clin Exp Immunol 181(3):457-67. doi: 10.1111/cei.12645. Epub 2015 Jul 19.
2015
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| 21 | CD14, TLR4
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| LPS receptor subunits have antagonistic roles in epithelial apoptosis and colonic carcinogenesis.
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| Kuo WT, Lee TC, Yang HY, Chen CY, Au YC, Lu YZ, Wu LL, Wei SC, Ni YH, Lin BR, Chen Y, Tsai YH, Kung JT, Sheu F, Lin LW, Yu LC.
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| Cell Death Differ 22(10):1590-604. doi: 10.1038/cdd.2014.240. Epub 2015 Jan 30.
2015
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| 22 | CD14, CD33, TLR4
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| Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33.
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| Ishida A, Akita K, Mori Y, Tanida S, Toda M, Inoue M, Nakada H.
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| J Biol Chem 289(36):25341-50. doi: 10.1074/jbc.M113.523480. Epub 2014 Jul 24.
2014
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| 23 | CD14
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| Ingested soluble CD14 contributes to the functional pool of circulating sCD14 in mice.
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| Ward TL, Goto K, Altosaar I.
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| Immunobiology 219(7):537-46. doi: 10.1016/j.imbio.2014.03.008. Epub 2014 Mar 20.
2014
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| 24 | CD14, LGR4
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| Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression.
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| Du B, Luo W, Li R, Tan B, Han H, Lu X, Li D, Qian M, Zhang D, Zhao Y, Liu M.
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| J Biol Chem 288(21):15131-41. doi: 10.1074/jbc.M113.455535. Epub 2013 Apr 15.
2013
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| 25 | CD14
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| CD14 mediates binding of high doses of LPS but is dispensable for TNF-α production.
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| Borzęcka K, Płóciennikowska A, Björkelund H, Sobota A, Kwiatkowska K.
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| Mediators Inflamm 2013:824919. doi: 10.1155/2013/824919. Epub 2013 Dec 30.
2013
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| 26 | CD14
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| CD14 regulates gastric cancer cell epithelial‑mesenchymal transition and invasion in vitro.
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| Li K, Dan Z, Hu X, Gesang L, Ze Y, Bianba Z.
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| Oncol Rep 30(6):2725-32. doi: 10.3892/or.2013.2733. Epub 2013 Sep 19.
2013
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| 27 | CD14
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| Association between tuberculosis and atopy: role of the CD14-159C/T polymorphism.
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| Baççioğlu Kavut A, Kalpaklioğlu F, Birben E, Ayaslioğlu E.
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| J Investig Allergol Clin Immunol 22(3):201-7. Erratum in: J Investig Allergol Clin Immunol. 2012;22(5):393.
2012
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| 28 | CD14
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| Differential expression of CD14-dependent and independent pathways for chemokine induction regulates neutrophil trafficking in infection.
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| Metkar S, Kim KS, Silver J, Goyert SM.
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| J Leukoc Biol 92(2):389-96. doi: 10.1189/jlb.0112011. Epub 2012 May 16.
2012
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| 29 | CD14
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| Cd14 SNPs regulate the innate immune response.
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| Liu HH, Hu Y, Zheng M, Suhoski MM, Engleman EG, Dill DL, Hudnall M, Wang J, Spolski R, Leonard WJ, Peltz G.
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| Mol Immunol 51(2):112-27. doi: 10.1016/j.molimm.2012.02.112. Epub 2012 Mar 23.
2012
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| 30 | CD14
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| CD14 modulates inflammation-driven insulin resistance.
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| Fernández-Real JM, Pérez del Pulgar S, Luche E, Moreno-Navarrete JM, Waget A, Serino M, Sorianello E, Sánchez-Pla A, Pontaque FC, Vendrell J, Chacón MR, Ricart W, Burcelin R, Zorzano A.
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| Diabetes 60(8):2179-86. doi: 10.2337/db10-1210. Epub 2011 Jun 23.
2011
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| 31 | CD14
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| Deletion of CD14 attenuates Alzheimer's disease pathology by influencing the brain's inflammatory milieu.
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| Reed-Geaghan EG, Reed QW, Cramer PE, Landreth GE.
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| J Neurosci. 30(46):15369-73. 2010
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| 32 | CD14, CXCL5, CXCR2
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| Adipose tissue-derived stem cells secrete CXCL5 cytokine with chemoattractant and angiogenic properties.
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| Zhang H, Ning H, Banie L, Wang G, Lin G, Lue TF, Lin CS.
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| Biochem Biophys Res Commun 402(3):560-4. Epub 2010 Oct 27.
2010
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| 33 | CD14
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| CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation.
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| Zanoni I, Ostuni R, Capuano G, Collini M, Caccia M, Ronchi AE, Rocchetti M, Mingozzi F, Foti M, Chirico G, Costa B, Zaza A, Ricciardi-Castagnoli P, Granucci F.
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| Nature 460(7252):264-8. doi: 10.1038/nature08118. Epub 2009 Jun 14.
2009
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| 34 | CD14
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| Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling.
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| Rallabhandi P, Bell J, Boukhvalova MS, Medvedev A, Lorenz E, Arditi M, Hemming VG, Blanco JC, Segal DM, Vogel SN.
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| J Immunol 177(1):322-32. 2006
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| 35 | CD14
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| Double-stranded RNA-mediated TLR3 activation is enhanced by CD14.
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| Lee HK, Dunzendorfer S, Soldau K, Tobias PS.
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| Immunity. 24(2):153-63. 2006
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| 36 | TLR2, CD14
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| The CD14 region spanning amino acids 57-64 is critical for interaction with the extracellular Toll-like receptor 2 domain.
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| Iwaki D, Nishitani C, Mitsuzawa H, Hyakushima N, Sano H, Kuroki Y.
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| Biochem Biophys Res Commun 328(1):173-6. 2005
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| 37 | CD14
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| Association of the CD14 gene -159C polymorphism with progression of IgA nephropathy
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| Yoon HJ, Shin JH, Yang SH, Chae DW, Kim H, Lee DS, Kim HL, Kim S, Lee JS, Kim YS.
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| J Med Genet 40(2):104-8. 2003
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| 38 | CD14, NOD2
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| Interaction of polymorphisms in the CARD15 and CD14 genes in patients with Crohn disease.
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| Klein W, Tromm A, Griga T, Folwaczny C, Hocke M, Eitner K, Marx M, Duerig N, Epplen JT.
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| Scand J Gastroenterol 38(8):834-6. 2003
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| 39 | CD14
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| A prospective evaluation of the CD14 and CD18 gene polymorphisms and risk of stroke.
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| Zee RY, Bates D, Ridker PM.
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| Stroke 33(4):892-5. 2002
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| 40 | CD14
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| Promoter polymorphisms in the CD14 receptor gene and their potential association with the severity of chronic periodontitis.
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| Holla LI, Buckova D, Fassmann A, Halabala T, Vasku A, Vacha J.
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| J Med Genet 39(11):844-8. No abstract available. 2002
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| 41 | CD14, LBP, MAPK11, MAPK12, MAPK13
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| Lipopolysaccharide-binding protein- and CD14-dependent activation of mitogen-activated protein kinase p38 by lipopolysaccharide in human neutrophils is associated with priming of respiratory burst.
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| Yan SR, Al-Hertani W, Byers D, Bortolussi R.
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| Infect Immun 70(8):4068-74. 2002
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| 42 | CD14
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| CD14-dependent activation of NF-kappaB by filarial parasitic sheath proteins.
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| Narayanan K, Seufzer BJ, Brockman-Schneider RA, Gern JE, Balakrishnan A, Miyamoto S.
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| Cell Biol Int 26(1):43-54. 2002
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| 43 | CD14, LBP, TLR4
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| TLR4-dependent recognition of lipopolysaccharide by epithelial cells requires sCD14.
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| Backhed F, Meijer L, Normark S, Richter-Dahlfors A.
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| Cell Microbiol 4(8):493-501. 2002
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| 44 | CD14, LY96, TLR4
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| Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
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| Latz E, Visintin A, Lien E, Fitzgerald KA, Monks BG, Kurt-Jones EA, Golenbock DT, Espevik T.
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| J Biol Chem 277(49):47834-43. 2002
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| 45 | CD14
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| A polymorphism in the CD14 gene is associated with Crohn disease.
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| Klein W, Tromm A, Griga T, Fricke H, Folwaczny C, Hocke M, Eitner K, Marx M, Duerig N, Epplen JT.
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| Scand J Gastroenterol 37(2):189-91. 2002
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| 46 | CD14
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| Lipopolysaccharide and ceramide docking to CD14 provokes ligand-specific receptor clustering in rafts.
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| Pfeiffer A, Böttcher A, Orsó E, Kapinsky M, Nagy P, Bodnár A, Spreitzer I, Liebisch G, Drobnik W, Gempel K, Horn M, Holmer S, Hartung T, Multhoff G, Schütz G, Schindler H, Ulmer AJ, Heine H, Stelter F, Schütt C, Rothe G, Szöllôsi J, Damjanovich S, Schmitz G.
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| Eur J Immunol. 31(11):3153-64. 2001
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| 47 | CD14
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| Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex.
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| Baveye S, Elass E, Fernig DG, Blanquart C, Mazurier J, Legrand D.
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| Infect Immun. 68(12):6519-25. 2000
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| 48 | CD14
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| A Polymorphism* in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E.
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| Baldini M, et al.
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| Am J Respir Cell Mol Biol 20(5):976-83. 1999
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| 49 | CD14
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| C(-260)-->T polymorphism in the promoter of the CD14 monocyte receptor gene as a risk factor for myocardial infarction.
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| Hubacek JA, et al.
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| Circulation 99(25):3218-20 1999
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| 50 | CD14
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| Human CD14 mediates recognition and phagocytosis of apoptotic cells.
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| Devitt A, et al.
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| Nature 392 : 505-509. 1998
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| 51 | CD14
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| CD14 is a cell-activating receptor for bacterial peptidoglycan.
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| Gupta D, Kirkland TN, Viriyakosol S, Dziarski R.
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| J Biol Chem. 271(38):23310-6. 1996
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| 52 | CD14
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| Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice.
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| Haziot A, Ferrero E, Köntgen F, Hijiya N, Yamamoto S, Silver J, Stewart CL, Goyert SM.
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| Immunity. 4(4):407-14. 1996
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| 53 | CD14
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| LPS-dependent interaction of Mac-2-binding protein with immobilized CD14.
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| Yu B, Wright SD.
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| J Inflamm. 45(2):115-25. 1995
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| 54 | ADRB2, CD14, CSF1R, FGF1, GABRA1, IL3, IL9, GABRG2
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| A radiation hybrid map of 18 growth factor , growth factor receptor, hormone receptor, or neurotransmitter receptor genes on the distal region of the long arm of chromosome 5.
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| Warrington JA, et al.
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| Genomics 13 : 803-808. 1992
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| 55 | CD14
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| The CD14 monocyte differenciation antigen maps to a region encoding growth factors and receptors.
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| Goyert SM, et al.
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| Science 239 : 497-500. 1988
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| 56 | CD14
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| Evidence of a trimolecular complex involving LPS, LPS binding protein and soluble CD14 as an effector of LPS response.
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| Thomas CJ, Kapoor M, Sharma S, Bausinger H, Zyilan U, Lipsker D, Hanau D, Surolia A.
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| FEBS Lett. 531(2):184-8.
|