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FLASH GENE

Symbol

IL5

contributors: mct - updated : 08-02-2023

HGNC name	interleukin 5 (colony-stimulating factor, eosinophil)
HGNC id	6016

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --other   dysregulation of IL5 production in peripheral blood mononuclear cells (PBMC) in familial eosinophilia (FE)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	the early detection of multiple plasma cytokines might help to predict the prognosis of COVID-19
Therapy target
	System Type Disorder Pubmed allergy asthm   is a suitable target for add-on biological therapies based on IL5 inhibition for patients with severe type 2 (T2)-high eosinophilic asthma, refractory to conventional anti-inflammatory drugs

ANIMAL & CELL MODELS