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FLASH GENE

Symbol

F2RL1

contributors: mct/npt - updated : 24-10-2016

HGNC name	coagulation factor II (thrombin) receptor-like 1
HGNC id	3538

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       gain of function induced the redistribution of COPS5 from the plasma membrane to the cytosol, but did not influence expression of COPS5

Susceptibility

to arthritis to atopic dermatitis

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed miscelleaneous urinary chronic kidney disease F2RL1 antagonists could be useful disease-modifying, anti-inflammatory agents in kidney disease

ANIMAL & CELL MODELS