Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SLC6A7 contributors: mct - updated : 16-02-2008
HGNC name solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
HGNC id 11054
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 12 transmembrane segments (12TM)
    • HOMOLOGY
    Homologene
    FAMILY
  • sodium:neurotransmitter symporter (SNF) family
    • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    text located in synaptosomal membranes
    basic FUNCTION
  • Na+ (and Cl-) dependent plasma membrane transporter of proline, high affinity
  • playing a presynaptic regulatory role in excitatory synaptic transmission
  • transporter for an excitatory neurotransmitter of L-proline
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to asthma
    Variant & Polymorphism other significant associations between genetic variants of the SLC6A7 gene and asthma
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS