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FLASH GENE

Symbol

SLC26A2

contributors: mct/npt - updated : 28-02-2014

HGNC name	solute carrier family 26 (sulfate transporter), member 2
HGNC id	10994

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

ACG1B , ATSG2 , DTD , EDM4

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

	Nephrolithiasis in the Slc26a6(-/-) mouse is accompanied by 50-75p100 reduction in intestinal oxalate secretion with unchanged intestinal oxalate absorption
	collagen fibrils in bone were thinner and less organized in dtd compared to wild-type mice, suggesting that the low bone mass observed in mutant mice could possibly be linked to the different bone matrix compositions/organizations in dtd mice triggering changes in osteoblast and osteoclast activities