Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

HBEGF

contributors: mct - updated : 28-04-2016

HGNC name	heparin-binding EGF-like growth factor
HGNC id	3059

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   in preeclampsia and in fetal growth retardation constitutional     --low   in smooth muscle or endothelial cell lineages causes heart malformation tumoral     --over   in ovarian, gastric, and breast cancer, melanoma and glioblastoma cells

Susceptibility

to dyphteria toxin

Variant & Polymorphism

Candidate gene	marker of the keratinocyte's response to a challenging environment and this growth factor alters the phenotype of keratinocytes in a manner similar to that observed during epidermal repair
Marker
Therapy target
	System Type Disorder Pubmed cancer     cancer therapy

ANIMAL & CELL MODELS