| 1 | AKT1, FSCN1, HBEGF, SOX2
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| SOX2 Promotes Brain Metastasis of Breast Cancer by Upregulating the Expression of FSCN1 and HBEGF
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| Xiao W, Zheng S, Xie X, Li X, Zhang L, Yang A, Wang J, Tang H, Xie X.
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| Mol Ther Oncolytics. Mar 13;17:118-129. doi: 10.1016/j.omto.2020.03.001. 2020
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| 2 | HAS1, HAS3, HBEGF
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| Hyaluronan metabolism in human keratinocytes and atopic dermatitis skin is driven by a balance of hyaluronan synthases 1 and 3.
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| Malaisse J, Bourguignon V, De Vuyst E, Lambert de Rouvroit C, Nikkels AF, Flamion B, Poumay Y.
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| J Invest Dermatol 134(8):2174-82. doi: 10.1038/jid.2014.147. Epub 2014 Mar 21.
2014
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| 3 | EOB, HBEGF, LGR4
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| GPR48-Induced keratinocyte proliferation occurs through HB-EGF mediated EGFR transactivation.
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| Wang Z, Jin C, Li H, Li C, Hou Q, Liu M, Dong Xda E, Tu L.
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| FEBS Lett 584(18):4057-62. Epub 2010 Aug 21.
2010
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| 4 | HBEGF, PTGS2, ST6GALNAC5
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| Genes that mediate breast cancer metastasis to the brain.
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| Bos PD, Zhang XH, Nadal C, Shu W, Gomis RR, Nguyen DX, Minn AJ, van de Vijver MJ, Gerald WL, Foekens JA, Massagué J.
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| Nature 459(7249):1005-9. Epub 2009 May 6.PMID: 19421193 2009
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| 5 | HBEGF
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| Heparin-binding EGF-like growth factor is induced by disruption of lipid rafts and oxidative stress in keratinocytes and participates in the epidermal response to cutaneous wounds.
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| Mathay C, Giltaire S, Minner F, Bera E, HŽrin M, Poumay Y.
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| J Invest Dermatol 128(3):717-27. Epub 2007 Oct 11. 2008
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| 6 | AREG, HBEGF
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| Validation of HB-EGF and amphiregulin as targets for human cancer therapy.
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| Yotsumoto F, Yagi H, Suzuki SO, Oki E, Tsujioka H, Hachisuga T, Sonoda K, Kawarabayashi T, Mekada E, Miyamoto S.
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| Biochem Biophys Res Commun 365(3):555-61. Epub 2007 Nov 20.
2008
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| 7 | HBEGF
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| Loss of HB-EGF in smooth muscle or endothelial cell lineages causes heart malformation.
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| Nanba D, Kinugasa Y, Morimoto C, Koizumi M, Yamamura H, Takahashi K, Takakura N, Mekada E, Hashimoto K, Higashiyama S.
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| Biochem Biophys Res Commun 350(2):315-21. Epub 2006 Sep 22. 2006
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| 8 | HBEGF
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| Pre-eclampsia and expression of heparin-binding EGF-like growth factor.
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| Leach RE, Romero R, Kim YM, Chaiworapongsa T, Kilburn B, Das SK, Dey SK, Johnson A, Qureshi F, Jacques S, Armant DR.
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| Lancet 360(9341):1215-9. 2002
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| 9 | HBEGF
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| Structural organization and chromosomal assignment of the gene encoding the human heparin-binding epidermal growth factor-like growth factor/diphteria toxin receptor.
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| Fen Z, et al.
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| Biochemistry 32 : 7932-7938. 1993
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| 10 | HBEGF
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| Expression cloning of a diphtheria toxin receptor : identity with a heparin-binding EGF-like growth factor precursor.
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| Naglich JG, et al.
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| Cell 69 : 1051-1061. 1992
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| 11 | HBEGF
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| Regional assignment of the gene for diphtheria toxin sensitivity using subchromosomal fragments in microcell hybrids.
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| Hayes H, et al.
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| Chromosoma 96 : 26-32. 1987
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| 12 | HBEGF
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| Diphtheria toxin sensitivity in a monochromosomal hybrid containing human chromosome 5.
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| Athwal RS, et al.
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| J Hered 76 : 329-334. 1985
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| 13 | HBEGF
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| Chromosome assignments of genes in man using mouse-human somatic cell hybrids: association of diphtheria toxin sensitivity with chromosome 5.
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| Creagan RP, et al.
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| Cytogenet Cell Genet 14 : 109-111. 1975
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| 14 | HBEGF
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| Genetic analysis of the cell surface: association of human chromosome 5 with sensitivity to diphtheria toxin in mouse-human somatic cell hybrids.
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| Creagan RP, et al.
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| Proc Natl Acad Sci U S A 72 : 2237-2241. 1975
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| 15 | HBEGF
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| Genetic analysis of the cell surface: assignment to human chromosome 5 of a gene(s) that confers sensitivity to diphteria toxin in mouse-human somatic cell hybrids.
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| Creagan RP, et al.
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| Am J Hum Genet 26 : 24A. 1974
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