| Other morbid association(s)
|
| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| tumoral
|
|
| --low
|
| |
in breast cancer | | tumoral
|
|
| --over
|
| |
in invasive adenocarcinoma | | constitutional
|
|
|
|
| |
silencing of PHB blocks the formation of functional blood vessels (Schleicher 2008) | | constitutional
|
|
| --low
|
|
loss of PHB in spermatocytes resulted in complete male infertility, associated with not only meiotic pachytene arrest with accompanying apoptosis, but also apoptosis resulting from mitochondrial morphology and function impairment  | |
