| 1 | PHB, STAG3
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| PHB regulates meiotic recombination via JAK2-mediated histone modifications in spermatogenesis.
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| Zhang LF, Tan-Tai WJ, Li XH, Liu MF, Shi HJ, Martin-DeLeon PA, O WS, Chen H.
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| Nucleic Acids Res. May 21;48(9):4780-4796. doi: 10.1093/nar/gkaa203. 2020
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| 2 | KDELR1, KDELR2, PHB
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| Prohibitin: A Novel Molecular Player in KDEL Receptor Signalling.
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| Giannotta M, Fragassi G, Tamburro A, Vanessa C, Luini A, Sallese M.
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| Biomed Res Int 2015:319454. doi: 10.1155/2015/319454. Epub 2015 May 10.
2015
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| 3 | CD86, IGHG1, PHB, PHB2
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| Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes.
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| Lucas CR, Cordero-Nieves HM, Erbe RS, McAlees JW, Bhatia S, Hodes RJ, Campbell KS, Sanders VM.
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| J Immunol 190(2):723-36. doi: 10.4049/jimmunol.1201646. Epub 2012 Dec 12.
2013
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| 4 | PHB, PHB2, SIGLEC9
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| Prohibitins function as endogenous ligands for Siglec-9 and negatively regulate TCR signaling upon ligation
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| Yurugi H, Tanida S, Akita K, Ishida A, Toda M, Nakada H.
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| Biochem Biophys Res Commun. May 3;434(2):376-81. doi: 10.1016/j.bbrc.2013.03.085. Epub 2013 Apr 6 2013
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| 5 | PHB, SKP2, TP53
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| Skp2B attenuates p53 function by inhibiting prohibitin.
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| Chander H, Halpern M, Resnick-Silverman L, Manfredi JJ, Germain D.
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| EMBO Rep 11(3):220-5. Epub 2010 Feb 5.
2010
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| 6 | PHB, PHB2
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| Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein.
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| Emerson V, Holtkotte D, Pfeiffer T, Wang IH, Schnölzer M, Kempf T, Bosch V.
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| J Virol 84(3):1355-65. Epub 2009 Nov 11.PMID: 19906925 2010
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| 7 | PHB, PHB2
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| Prohibitins and the functional compartmentalization of mitochondrial membranes.
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| Osman C, Merkwirth C, Langer T.
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| J Cell Sci 122(Pt 21):3823-30. Review.PMID: 19889967 2009
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| 8 | PHB, PHB2
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| The PHB1/2 phosphocomplex is required for mitochondrial homeostasis and survival of human T cells.
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| Ross JA, Nagy ZS, Kirken RA.
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| J Biol Chem 283(8):4699-713. Epub 2007 Dec 17.PMID: 18086671 2008
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| 9 | PHB
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| Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence.
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| Schleicher M, Shepherd BR, Suarez Y, Fernandez-Hernando C, Yu J, Pan Y, Acevedo LM, Shadel GS, Sessa WC.
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| J Cell Biol 180(1):101-12.PMID: 18195103 2008
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| 10 | PHB, TFAM
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| Human prohibitin 1 maintains the organization and stability of the mitochondrial nucleoids.
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| Kasashima K, Sumitani M, Satoh M, Endo H.
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| Exp Cell Res 314(5):988-96. Epub 2008 Jan 16.PMID: 18258228 2008
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| 11 | YY1, PHB, E2F1, TP53, CASP7
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| Differential regulation of human YY1 and caspase 7 promoters by prohibitin through E2F1 and p53 binding sites.
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| Joshi B, Rastogi S, Morris M, Carastro LM, DeCook C, Seto E, Chellappan SP.
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| Biochem J 401(1):155-66. 2007
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| 12 | NPHS2, STOM, STOML1, PHB
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| The significance of prohibitin and c-Met/hepatocyte growth factor receptor in the progression of cervical adenocarcinoma.
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| Tsai HW, Chow NH, Lin CP, Chan SH, Chou CY, Ho CL.
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| Hum Pathol 37(2):198-204. Epub 2005 Dec 20. 2006
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| 13 | PHB
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| Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration.
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| Rajalingam K, Wunder C, Brinkmann V, Churin Y, Hekman M, Sievers C, Rapp UR, Rudel T.
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| Nat Cell Biol 7(8):837-43. Epub 2005 Jul 24. 2005
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| 14 | PHB
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| Prohibitin: a potential target for new therapeutics.
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| Mishra S, Murphy LC, Nyomba BL, Murphy LJ.
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| Trends Mol Med 11(4):192-7. Review. 2005
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| 15 | PHB
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| Expression of prohibitin 3' untranslated region suppressor RNA alters morphology and inhibits motility of breast cancer cells.
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| Manjeshwar S, Lerner MR, Zang XP, Branam DE, Pento JT, Lane MM, Lightfoot SA, Brackett DJ, Jupe ER.
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| J Mol Histol 35(6):639-46. 2004
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| 16 | PSEN1, PHB, NCSTN, PSENEN, APH1A
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| Purification and characterization of the human gamma-secretase complex.
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| Fraering PC, Ye W, Strub JM, Dolios G, LaVoie MJ, Ostaszewski BL, van Dorsselaer A, Wang R, Selkoe DJ, Wolfe MS.
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| Biochemistry 43(30):9774-89. 2004
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| 17 | PHB
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| Tumor suppression by the prohibitin gene 3'untranslated region RNA in human breast cancer.
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| Manjeshwar S, Branam DE, Lerner MR, Brackett DJ, Jupe ER.
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| Cancer Res 63(17):5251-6. 2003
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| 18 | E2F1, PHB
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| A putative coiled-coil domain of prohibitin is sufficient to repress E2F1-mediated transcription and induce apoptosis.
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| Joshi B, Ko D, Ordonez-Ercan D, Chellappan SP.
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| Biochem Biophys Res Commun 312(2):459-66. 2003
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| 19 | E2F1, PHB, RB1
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| Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function.
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| Wang S, Nath N, Adlam M, Chellappan S.
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| Oncogene 18(23):3501-10. 1999
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| 20 | ATP6V0A1, GIP, GNGT2, B4GALNT2, CALCOCO2, PDK2, PHB, SLC35B1, IGFBP2
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| Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level.
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| Mohlke KL, et al.
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| Genomics 54 : 19-30. 1998
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| 21 | D5S141, D11S576, D11S740, D17S1176, D17S570, PHB
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| Six microsatellite polymorphisms at candidate and confirmed tumour suppressor gene loci.
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| Jones MH, et al.
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| Hum Mol Genet 3 : 1911. 1994
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| 22 | PHB, PHBP1, PHBP2, PHBP3, PHBP4
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| The human prohibitin (PHB) gene family and its somatic mutations in human tumors.
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| Sato T, et al.
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| Genomics 17 : 762-764. 1993
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| 23 | PHB
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| Assignment of the human prohibitin gene (PHB) to chromosome 17 and identification of a DNA polymorphism.
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| White JJ, et al.
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| Genomics 11 : 228-230. 1991
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| 24 | PHB
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| Assignment of the human prohibitin gene (PHB) to chromosome 17q21.
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| White JJ, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 2011. 1991
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