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FLASH GENE

Symbol

MUC4

contributors: np/mct - updated : 11-03-2011

HGNC name	mucin 4, cell surface associated
HGNC id	7514

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in pancreatic carcinoma tumoral     --low   in ovarian epithelial cancer with increased cancer stage tumoral     --other   aberrantly expressed in 75p100 of pancreatic ductal adenocarcinomas tumoral     --over   in ovarian tumors and has a role in the invasiveness of OC cells tumoral     --over   in squamous cervical dysplasia and carcinomas

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	useful biological marker for the diagnosis of ductal adenocarcinomas
	lineage marker in benign cervical tissue
Therapy target
	System Type Disorder Pubmed cancer digestive oesophagus MUC1 and MUC4 may be attractive targets for the selection of treatment methods in oral squamous cell carcinoma (OSCC)

ANIMAL & CELL MODELS