Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

LMO2

contributors: mct - updated : 10-09-2016

HGNC name	LIM domain only 2 (rhombotin-like 1)
HGNC id	6642

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral   translocation     acute lymphoblastic leukemia (T-ALL) with translocations t(11;14)(p13;q11), t(7;11)(p35;p13) tumoral       loss of function in renal clear cell carcinomas with poor prognosis tumoral fusion       t(14;18)/IGH-BCL2 fusion in diffuse large B-cell lymphoma

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	promising marker for predicting a better prognosis in pancreatic cancer
Therapy target
	System Type Disorder Pubmed cancer hemopathy   assembly of LMO2 into complexes, via direct LDB1 interaction, is a potential molecular target that could be exploited in LMO2-driven leukemias resistant to existing chemotherapy regimens

ANIMAL & CELL MODELS