| 1 | LMO2, UBA6, UBD, USE1
|
| LMO2 blocks the UBA6-USE1 interaction and downstream FAT10ylation by targeting the ubiquitin fold domain of UBA6.
|
| Wu C, Liu Y, Gu X, Zhu T, Yang S, Sun W.
|
| Biochem Biophys Res Commun 478(3):1442-8. doi: 10.1016/j.bbrc.2016.08.143. Epub 2016 Aug 26.
2016
|
| 2 | LDB1, LMO2
|
| LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding.
|
| Layer JH, Alford CE, McDonald WH, Davé UP.
|
| Mol Cell Biol 36(3):488-506. doi: 10.1128/MCB.00901-15. Print 2016 Feb 1.
2015
|
| 3 | GATA2, LMO2, NRP2
|
| GATA2 and Lmo2 control angiogenesis and lymphangiogenesis via direct transcriptional regulation of neuropilin-2.
|
| Coma S, Allard-Ratick M, Akino T, van Meeteren LA, Mammoto A, Klagsbrun M.
|
| Angiogenesis 16(4):939-52. doi: 10.1007/s10456-013-9370-9.
2013
|
| 4 | JAK2, LCK, LMO2
|
| Nuclear localization of lymphocyte-specific protein tyrosine kinase (Lck) and its role in regulating LIM domain only 2 (Lmo2) gene.
|
| Venkitachalam S, Chueh FY, Yu CL.
|
| Biochem Biophys Res Commun 417(3):1058-62. doi: 10.1016/j.bbrc.2011.12.095. Epub 2011 Dec 27.
2012
|
| 5 | CREBBP, KDM3B, LMO2
|
| KDM3B is the H3K9 demethylase involved in transcriptional activation of lmo2 in leukemia.
|
| Kim JY, Kim KB, Eom GH, Choe N, Kee HJ, Son HJ, Oh ST, Kim DW, Pak JH, Baek HJ, Kook H, Hahn Y, Kook H, Chakravarti D, Seo SB.
|
| Mol Cell Biol 32(14):2917-33. doi: 10.1128/MCB.00133-12. Epub 2012 May 21.
2012
|
| 6 | GATA1, LDB1, LMO2, TAL1
|
| Structure of the leukemia oncogene LMO2: implications for the assembly of a hematopoietic transcription factor complex.
|
| El Omari K, Hoosdally SJ, Tuladhar K, Karia D, Vyas P, Patient R, Porcher C, Mancini EJ.
|
| Blood 117(7):2146-56. Epub 2010 Nov 12.
2011
|
| 7 | LMO2
|
| Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies.
|
| Treanor LM, Volanakis EJ, Zhou S, Lu T, Sherr CJ, Sorrentino BP.
|
| Blood 117(20):5453-62. Epub 2011 Mar 22.
2011
|
| 8 | LMO2, TAL1
|
| A DNA-binding mutant of TAL1 cooperates with LMO2 to cause T cell leukemia in mice.
|
| Draheim KM, Hermance N, Yang Y, Arous E, Calvo J, Kelliher MA.
|
| Oncogene 30(10):1252-60. Epub 2010 Nov 8.
2011
|
| 9 | LMO2
|
| LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome.
|
| Malumbres R, Fresquet V, Roman-Gomez J, Bobadilla M, Robles EF, Altobelli GG, Calasanz MJ, Smeland EB, Aznar MA, Agirre X, Martin-Palanco V, Prosper F, Lossos IS, Martinez-Climent JA.
|
| Haematologica 96(7):980-6. Epub 2011 Apr 1.
2011
|
| 10 | LMO2
|
| Purification, crystallization and preliminary X-ray analysis of a fusion of the LIM domains of LMO2 and the LID domain of Ldb1.
|
| El Omari K, Porcher C, Mancini EJ.
|
| Acta Crystallogr Sect F Struct Biol Cryst Commun 66(Pt 11):1466-9. Epub 2010 Oct 28.
2010
|
| 11 | LMO2
|
| LMO2 promotes angiogenesis probably by up-regulation of bFGF in endothelial cells: an implication of its pathophysiological role in infantile haemangioma.
|
| Sun ZJ, Cai Y, Chen G, Wang R, Jia J, Chen XM, Zheng LW, Zhao YF.
|
| Histopathology 57(4):622-32. doi: 10.1111/j.1365-2559.2010.03676.x.
2010
|
| 12 | LMO2
|
| Expression of LMO2 is associated with t(14;18)/IGH-BCL2 fusion but not BCL6 translocations in diffuse large B-cell lymphoma.
|
| Durnick DK, Law ME, Maurer MJ, Natkunam Y, Levy R, Lossos IS, Kurtin PJ, McPhail ED.
|
| Am J Clin Pathol 134(2):278-81.
2010
|
| 13 | LMO2
|
| The expression of LMO2 protein in acute B-cell and myeloid leukemia.
|
| Cobanoglu U, Sonmez M, Ozbas HM, Erkut N, Can G.
|
| Hematology 15(3):132-4.
2010
|
| 14 | LMO2
|
| Regulation of LMO2 mRNA and protein expression in erythroid differentiation.
|
| Brandt SJ, Koury MJ.
|
| Haematologica 94(4):447-8. Review. No abstract available.
2009
|
| 15 | LMO2
|
| An antibody inhibitor of the LMO2-protein complex blocks its normal and tumorigenic functions.
|
| Nam CH, Lobato MN, Appert A, Drynan LF, Tanaka T, Rabbitts TH.
|
| Oncogene 27(36):4962-8. Epub 2008 Apr 28.
2008
|
| 16 | LMO2
|
| The Lim-only protein LMO2 acts as a positive regulator of erythroid differentiation.
|
| Hansson A, Zetterblad J, van Duren C, Axelson H, Jšnsson JI.
|
| Biochem Biophys Res Commun 364(3):675-81. Epub 2007 Oct 22. 2007
|
| 17 | LMO2
|
| The Lim-only protein LMO2 acts as a positive regulator of erythroid differentiation.
|
| Hansson A, Zetterblad J, van Duren C, Axelson H, Jönsson JI.
|
| Biochem Biophys Res Commun 364(3):675-81. Epub 2007 Oct 22.
2007
|
| 18 | LMO2, TALL
|
| The cryptic chromosomal deletion del(11)(p12p13) as a new activation mechanism of LMO2 in pediatric T-cell acute lymphoblastic leukemia.
|
| Van Vlierberghe P, van Grotel M, Beverloo HB, Lee C, Helgason T, Buijs-Gladdines J, Passier M, van Wering ER, Veerman AJ, Kamps WA, Meijerink JP, Pieters R.
|
| Blood 108(10):3520-9. Epub 2006 Jul 27.
2006
|
| 19 | BEX2, LMO2, NHLH2
|
| Human Bex2 interacts with LMO2 and regulates the transcriptional activity of a novel DNA-binding complex.
|
| Han C, Liu H, Liu J, Yin K, Xie Y, Shen X, Wang Y, Yuan J, Qiang B, Liu YJ, Peng X.
|
| Nucleic Acids Res 33(20):6555-65. Print 2005. 2005
|
| 20 | LMO2
|
| A PAR domain transcription factor is involved in the expression from a hematopoietic-specific promoter for the human LMO2 gene.
|
| Crable SC, Anderson KP.
|
| Blood 101(12):4757-64. Epub 2003 Feb 27. 2003
|
| 21 | LMO4, LMO2, NHLH1, LMO4, CSRP3
|
| The LIM-only protein LMO4 modulates the transcriptional activity of HEN1.
|
| Manetopoulos C, Hansson A, Karlsson J, Jonsson JI, Axelson H.
|
| Biochem Biophys Res Commun 307(4):891-9. 2003
|
| 22 | LMO2
|
| The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice.
|
| Yamada Y, Pannell R, Forster A, Rabbitts TH.
|
| Proc Natl Acad Sci U S A 97(1):320-4 2000
|
| 23 | LMO2
|
| Promoter 1 of LMO2, a master gene for hematopoiesis, is regulated by the erythroid specific transcription factor GATA1.
|
| Pruess MM, Drechsler M, Royer-Pokora B.
|
| Gene Funct Dis 2 : 87-94. 2000
|
| 24 | LMO2
|
| The effect of chromosomal translocations in acute leukemias: the LMO2 paradigm in transcription and development.
|
| Rabbitts TH, et al.
|
| Cancer Res 59(7 Suppl):1794s-1798s. 1999
|
| 25 | LMO2, TAL1, ALDH1A2
|
| TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3.
|
| Ono Y, Fukuhara N, Yoshie O.
|
| Mol Cell Biol 18(12):6939-50. 1998
|
| 26 | KDM5A, LMO2
|
| T-cell oncogene rhombotin-2 interacts with retinoblastoma-binding protein 2.
|
| Mao S, Neale GA, Goorha RM.
|
| Oncogene 14(13):1531-9. 1997
|
| 27 | LMO2
|
| A high-resolution physical map of human chromosome 11.
|
| Qin S, et al.
|
| Proc Natl Acad Sci U S A 93 : 3149-3154. 1996
|
| 28 | LMO2
|
| The TTG-2/RBTN2 T cell oncogene encodes two alternative transcripts from two promoters : the distal promoter is removed by most 11p13 translocations in acute T cell leukaemia's (T-ALL).
|
| Royer-Pokora B, et al.
|
| Oncogene 10 : 1353-1360. 1995
|
| 29 | LMO2
|
| Rhom-2 expression does not always correlate with abnormalities on chromosome 11 at band p13 in T-cell acute lymphoblastic leukemia.
|
| Fitzgerald TJ, et al.
|
| Blood 80 : 3189-3197. 1992
|
| 30 | LMO1, LMO2
|
| The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13.
|
| Boehm T, et al.
|
| Proc Natl Acad Sci U S A 88 : 4367-4371. 1991
|
| 31 | LMO2
|
| TTG-2, a new gene encoding a cysteine-rich protein with the LIM motif, is overexpressed in acute T-cell leukaemia with the t(11;14)(p13;q11).
|
| Royer-Pokora B, et al.
|
| Oncogene 6 : 1887-1893. 1991
|
| 32 | LMO2
|
| A study of chromosome 11p13 translocations involving TCRbeta and TCRdelta in human T cell leukaemia.
|
| Sanchez Garcia I, et al.
|
| Oncogene 6 : 577-582. 1991
|
| 33 | LMO2
|
| An STS in the human T-ALL breakpoint cluster region (T-Allbcr) located at 11p13.
|
| Boehm T, et al.
|
| Nucleic Acids Res 18 : 4298. 1990
|
| 34 | TRD@, LMO2
|
| Multiple methylation-free islands flank a small breakpoint cluster region on 11p13 in the t(11;14)(p13;q11) translocation.
|
| Foroni L, et al.
|
| Genes Chromosomes Cancer 1 : 301-309. 1990
|
| 35 | TRD@, LMO2
|
| Molecular cloning of the translocation breakpoint in T-ALL 11;14 (p13;q11) : genomic map of TCR alpha and delta region on chromosome 14q11 and long-range map of region 11p13.
|
| Royer-Pokora B, Fleischer B, Ragg S, Loos U, Williams D.
|
| Hum Genet 82 : 264-270. 1989
|
| 36 | D11S289, LMO2
|
| Refined breakpoint map of WAGR and related patients with chromosome 11p13 markers.
|
| van Heyningen V, et al.
|
| (HGM10) Cytogenet Cell Genet 51 : 1095. 1989
|
| 37 | TRD@, LMO2
|
| The cell receptor delta chain locus is disrupted in the T-ALL associated t(11;14)(p13;q11) translocation.
|
| Champagne E, et al.
|
| Blood 73 : 1672-1676. 1989
|
| 38 | WT1, LMO2, TRD@
|
| The chromosome 11 region flanking the t(11;14) breakpoint in human T-ALL is deleted in Wilms' tumor hybrids.
|
| Finver SN, et al.
|
| Oncogene Res 5 : 143-148. 1989
|
| 39 | TRD@, LMO2
|
| The chromosome translocation (11;14)(p13;q11) associated with T-cell acute lymphocytic leukemia: an 11p13 breakpoint cluster region.
|
| Yoffe G, et al.
|
| Blood 74 : 374-379. 1989
|
| 40 | TRD@, LMO2
|
| The T-ALL specific t(11;14)(p13;q11) translocation breakpoint cluster region is located near to the Wilms' tumour predisposition locus.
|
| Boehm T, et al.
|
| Oncogene 3 : 691-695. 1988
|
| 41 | TRD@, LMO2
|
| (11;14) translocation in three boys with acute lymphoblastic leukemia of T-cell immunophenotype.
|
| Harbott J, Engel R, Gerein V, Schwamborn D, Rudolph R, Lampert F.
|
| Blut 52 : 45-50. 1986
|