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FLASH GENE

Symbol

IL1RN

contributors: mct - updated : 02-06-2015

HGNC name	interleukin 1 receptor antagonist
HGNC id	6000

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

conjugated

GlycoP

HOMOLOGY

Homologene

FAMILY

IL-1 family

CATEGORY

signaling cytokine , receptor

SUBCELLULAR LOCALIZATION	extracellular
	intracellular

basic FUNCTION

interleukin 1,receptor antagonist

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to ankylosing spondylitis to Chronic kidney disease (CKD) and periodontitis (PD)

Variant & Polymorphism other	allele 2 of a VNTR increasing the risk of ankylosing spondylitis
	association of IL1RN alleles with susceptibility to CKD and PD

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS