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FLASH GENE

Symbol

IL1R1

contributors: mct/npt - updated : 24-06-2010

HGNC name	interleukin 1 receptor, type I
HGNC id	5993

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to osteoporotic fractures to schizophrenia and bipolar disorder

Variant & Polymorphism repeat	86bp repeat increased risk of osteoporotic fractures
	VNTR allele 2 increasing risk of schizophrenia and bipolar disorder

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed diabete     protective effect of IL1R1 antagonist on pancreatic beta-cell survival and function

ANIMAL & CELL MODELS