| basic FUNCTION
| nucleosomal binding protein altering the structure of the chromatin fiber and enhancing transcription, only from chromatin templates |
|
modulates the level of histone H2A phosphorylation |
|
modulating histone posttranslational modifications, and histone H3 phosphorylation |
|
alters the compaction of the chromatin fiber, increases the cellular sensitivity to ionizing radiation, optimizes the cellular response to ionizing radiation and to other tumorigenic event |
|
altering the equilibrium generated by the opposing enzymatic activities that continuously modify and de-modify the histone tails in nucleosomes |
|
playing a role on chromatin structure but does not affect SWI/SNF-dependent chromatin remodeling on either mononucleosomes or nucleosomal arrays |
|
abundant nucleosomal binding protein, that can affect both the chromatin higher order structure and the modification of nucleosomal histones, but it alters the expression of only a subset of genes  |
|
regulates the expression of particular genes via specific protein-protein interactions with transcription factors at target gene regulatory regions |
|
potently repress ATP-dependent chromatin remodeling by four different molecular motor proteins |
|
act in opposition to ATP-dependent chromatin remodeling factors to restrict nucleosome mobility |
|
nuclear proteins that bind to nucleosomes and alter the structure of chromatin |
|
play a role in global DNA repair expands the role of these proteins in the maintenance of genome integrity |
|
modulates the interaction of ATM with chromatin both before and after double-stranded breaks formation, thereby optimizing its activation |
|
is potentially part of the cellular machinery that modulates transcriptional fidelity by generating, maintaining, or preferentially interacting with specific sites in chromatin |
|
nucleosome-binding protein ubiquitously expressed in vertebrate cells, that preferentially binds to CpG island-containing promoters and affects the organization of nucleosomes |
|
HMGN1, 2, and 3, promote astrocyte differentiation of neural precursor cells (NPCs) during brain development |
|
HMGN1, HMGN2, HMGN3 are novel chromatin regulatory factors that control astrocyte fate decision/differentiation in parallel with or downstream of the JAK-STAT pathway |
|
contributes to antitumor immunity and it may offer an effective adjuvant to heighten responses to cancer vaccines |
