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FLASH GENE
Symbol GNAI2 contributors: mct - updated : 13-09-2017
HGNC name guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
HGNC id 4385
ANIMAL & CELL MODELS
  • Galpha(i2) (-/-) mice have a reduced ventricular effective refractory period and a predisposition to ventricular tachycardia when challenged with programmed electrical stimulation
  • lack of Gnai2 leads to dilative cardiomyopathy and increased mortality in Adrb1 overexpressing mice