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FLASH GENE
Symbol GIN1 contributors: mct - updated : 20-01-2009
HGNC name gypsy retrotransposon integrase 1
HGNC id 25959
DNA
TYPE functioning gene
STRUCTURE 34.14 kb     8 Exon(s)
MAPPING cloned Y linked N status provisional
Map cen - D5S2683 - D5S1604E - GIN1 - D5S456 - D5S409 - qter
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 3549 59.71 522 - 2001 11470852
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon   Homo sapiens
 stomach     Homo sapiens
Endocrineparathyroid   highly Homo sapiens
Nervousbrain     Homo sapiens
Urinarykidney     Homo sapiens
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumcardiac   Homo sapiens
Nervouscentral   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • characteristic H2C2, DDE, and GPY/F motifs found in many retroviral and retrotransposon integrases
  • HOMOLOGY
    interspecies ortholog to murine Gin1 (85 p100)
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • may be part of an analogous defense system, perhaps having contributed to the virtual absence of Ty3/Gypsy elements in mammalian genomes
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS