protein
| NCOA3 and NCOA6 coactivators |
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binds to a direct repeat of two hexanucleotides spaced by one nucleotide, as heterodimers with the retinoid X receptor (NR1H3) |
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hepatic ALAS1 is a new direct target for the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARA)  |
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interacting with CYP2J2 (activates the nuclear receptor PPARA)  |
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requires transcription coactivator PPAR-binding protein (PBP)/mediator subunit 1(MED1) for its transcriptional activity  |
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major involvement of the SIRT1-PPARA interaction in the protective role of SIRT1 against cardiac hypertrophy  |
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fatty acids act as ligands for PPARA, and the activated PPARA receptor then stimulates the transcription of genes encoding proteins involved in the uptake and/or metabolism of lipids, cholesterol, and glucose metabolism  |
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FNDC5 acts to induce UCP1 gene expression, at least in part, via PPARA  |
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DDIT3 is necessary for suppression of genes encoding the transcriptional master regulators of lipid metabolism: CEBPA, PPARA, and SREBF1  |
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feedback loop between MXIPL and PPARA plays an important role in the regulation of lipogenesis in brown adipocytes  |
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MECR is a binding protein of the nuclear hormone receptor peroxisome proliferator-activated receptor alpha (PPARA), but the presence of a cytosolic or nuclear isoform of MECR is necessary for functional interaction between MECR and PPARA  |
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PPARA controls IGF1 signalling through the up-regulation of hepatic IGFBP2 transcription during fasting  |
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specific drug-FABP1, FABP2 complexes can interact with PPARA to effect nuclear accumulation of FABP1, FABP2 and Nuclear hormone receptors (NHRs) activation  |
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EP300 interacts with PPARA through a conserved LXXLL motif and enhances its transcriptional activity  |
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ANGPTL6-mediated increase in PPARA expression resulted in increased FGF21 expression, thereby promoting beta-oxidation |
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PPARA is a transcription factor that transactivates SLC47A1  |