Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|
|
|
| gain of function
|
by elevated Ca2+(o) concentrations, such as those found near resorbing bone, produces an especially strong chemoattractant effect on bone metastatic breast cancer cells toward the Ca2+-rich environment  | tumoral
|
|
|
|
|
silenced by genetic and epigenetic mechanisms in unfavorable neuroblastomas  | constitutional
|
|
| --over
|
|
in inflammatory states, such as that associated with obesity  | tumoral
|
|
| --over
|
|
in lung cancer tissues with bone metastasis, higher than that in non-metastatic lung cancer tissues  | |