Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | INSM1 | contributors: mct/npt - updated : 13-05-2009 |
HGNC name | insulinoma-associated 1 |
HGNC id | 6090 |
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DNA |
TYPE | functioning gene |
SPECIAL FEATURE | gene in gene |
text | situated on the promoter region of the NEUROD1 gene |
STRUCTURE | 2.83 kb 1 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence | Promoter |
motif | repetitive sequence |
text structure | three putative E-boxes (approximately 361 bp) upstream of the transcription start site was sufficient to confer tissue-specific transcriptional activity |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| insulinoma and other neuroendocrine tumor cell lines, small cells lung cancer | fluid/secretion
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at STAGE |
physiological period | fetal |
Text | exclusively expressed in the foetal pancreas and nervous system, and in tumours of neuroendocrine origin |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | DNA associated , transcription factor |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,nucleus |
basic FUNCTION | |
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