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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

SON

contributors: mct - updated : 18-10-2016

HGNC name	SON DNA binding protein
HGNC id	11183

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

TOKIMS

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in acute megakaryoblastic leukemia of Down syndrome constitutional     --low   leads to severe impairment of spindle pole separation, microtubule dynamics, and genome integrity

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	short SON overexpression is a marker indicating aberrant transcriptional initiation in leukemia
Therapy target
	System Type Disorder Pubmed cancer digestive pancreas is a novel therapeutic molecular target for pancreatic cancer

ANIMAL & CELL MODELS