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FLASH GENE
Symbol ATP1A1 contributors: mct - updated : 21-02-2018
HGNC name ATPase, Na+/K+ transporting, alpha 1 polypeptide
HGNC id 799
ANIMAL & CELL MODELS
  • Dahl salt-sensitive (S) rats bearing Dahl salt-resistant wildtype ATP1A1 cDNA exhibited less rat salt-sensitive hypertension, less hypersensitive renal disease, and longer life span compared with Dahl S controls
  • hearts from heterozygous ATP1A1 mice (with a targeted disruption in the gene) are hyponcontractile