|
| CX3CR1(-/-) mice have a significant reduction in macrophage recruitment to the vessel wall and decreased atherosclerotic lesion formation  | |
Retinal microglial density, distribution, cellular morphology, and overall retinal tissue anatomy were not altered in young CX3CR1(-/-) mice |
|
deleting CX3CR1 in hAPP mice increased expression of inflammatory factors, such as TNF and IL6, and exacerbated plaque-independent neuronal dysfunction and cognitive deficits |
|
in Cx3cr1-deficient (CX3CR1(GFP/GFP) ) rd10 mice microglial infiltration into the photoreceptor layer was significantly augmented and associated with accelerated photoreceptor apoptosis and atrophy |